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1PHW

Crystal structure of KDO8P synthase in its binary complex with substrate analog 1-deoxy-A5P

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0008676molecular_function3-deoxy-8-phosphooctulonate synthase activity
A0009058biological_processbiosynthetic process
A0009103biological_processlipopolysaccharide biosynthetic process
A0016740molecular_functiontransferase activity
A0019294biological_processketo-3-deoxy-D-manno-octulosonic acid biosynthetic process
A0032991cellular_componentprotein-containing complex
A0042802molecular_functionidentical protein binding
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE ROB A 70
ChainResidue
APRO1115
AALA1116
APHE1117
ALYS1138
AARG1168
AHIS1202

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1q3n
ChainResidueDetails
AHIS1202

site_idMCSA1
Number of Residues3
DetailsM-CSA 614
ChainResidueDetails
AASN1026electrostatic stabiliser, hydrogen bond donor
ALYS1060electrostatic stabiliser, hydrogen bond donor
AASP1250electrostatic stabiliser, hydrogen bond acceptor

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PDB entries from 2024-11-06

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