Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 505 |
| Chain | Residue |
| A | TYR191 |
| A | GLN259 |
| A | LYS260 |
| A | THR262 |
| A | ARG287 |
| A | ARG446 |
| A | HOH528 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 508 |
| Chain | Residue |
| A | HIS248 |
| A | HOH524 |
| A | HOH636 |
| A | HOH899 |
| A | LYS50 |
| A | HIS212 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE NBP A 499 |
| Chain | Residue |
| A | GLY9 |
| A | LEU10 |
| A | ALA11 |
| A | VAL12 |
| A | MET13 |
| A | ASN32 |
| A | ARG33 |
| A | THR34 |
| A | VAL74 |
| A | LYS75 |
| A | PHE83 |
| A | GLY101 |
| A | ASN102 |
| A | GLU131 |
| A | POP506 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE POP A 506 |
| Chain | Residue |
| A | ASN102 |
| A | VAL127 |
| A | SER128 |
| A | GLY129 |
| A | GLY130 |
| A | LYS183 |
| A | ASN187 |
| A | ILE366 |
| A | NBP499 |
| A | HOH614 |
| A | HOH1051 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. IrDsaGQKGTGkW |
| Chain | Residue | Details |
| A | ILE253-TRP265 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | MET184 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | TYR191 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | BINDING: in other chain |
| Chain | Residue | Details |
| A | LEU10 | |
| A | CYS288 | |
| A | ARG33 | |
| A | LYS75 | |
| A | SER103 | |
| A | GLY129 | |
| A | GLU131 | |
| A | ASN187 | |
| A | GLY192 | |
| A | GLY261 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP447 | |
| A | THR453 | |
| A | SER478 | |
| Chain | Residue | Details |
| A | VAL38 | |
| Chain | Residue | Details |
| A | LEU57 | |
| A | GLY129 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2pgd |
| Chain | Residue | Details |
| A | ASN187 | |
| A | LYS183 | |
| A | GLY130 | |
| A | GLU190 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 889 |
| Chain | Residue | Details |
| A | GLY129 | electrostatic stabiliser, promote heterolysis |
| A | MET184 | proton acceptor, proton donor |
| A | ASN187 | electrostatic stabiliser, promote heterolysis |
| A | GLY188 | electrostatic stabiliser, promote heterolysis |
| A | TYR191 | proton acceptor, proton donor |
