1PG0
Methionyl-trna synthetase from escherichia coli complexed with methioninyl adenylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004825 | molecular_function | methionine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006431 | biological_process | methionyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE MOD A 553 |
| Chain | Residue |
| A | ALA12 |
| A | TRP253 |
| A | ALA256 |
| A | PRO257 |
| A | TYR260 |
| A | GLY294 |
| A | ASP296 |
| A | ILE297 |
| A | HIS323 |
| A | GLY324 |
| A | TYR325 |
| A | LEU13 |
| A | VAL326 |
| A | HOH1091 |
| A | HOH1187 |
| A | HOH1189 |
| A | HOH1191 |
| A | PRO14 |
| A | TYR15 |
| A | HIS21 |
| A | GLY23 |
| A | HIS24 |
| A | GLU27 |
| A | ASP52 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 12 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PyaNGsIHLGHM |
| Chain | Residue | Details |
| A | PRO14-MET25 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Motif: {"description":"'HIGH' region","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"'KMSKS' region","evidences":[{"source":"PubMed","id":"7932711","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11243794","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12946347","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F4L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1PG2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"2254937","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a8h |
| Chain | Residue | Details |
| A | LYS335 | |
| A | LYS332 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a8h |
| Chain | Residue | Details |
| A | LYS335 |
