Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 330 |
| Chain | Residue |
| A | TYR192 |
| A | GLN194 |
| A | ILE212 |
| A | GOL331 |
| A | HOH391 |
| A | HOH493 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 331 |
| Chain | Residue |
| A | PHE294 |
| A | ILE300 |
| A | GOL330 |
| A | HOH570 |
| A | LEU8 |
| A | ASP214 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 332 |
| Chain | Residue |
| A | THR81 |
| A | PHE167 |
| A | ARG176 |
| A | PHE177 |
| A | LEU329 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 330 |
| Chain | Residue |
| C | GLU78 |
| C | GLU150 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 331 |
| Chain | Residue |
| C | PHE167 |
| C | ARG176 |
| C | LEU329 |
| C | HOH468 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 330 |
| Chain | Residue |
| D | GLU207 |
| D | LYS208 |
| D | ALA209 |
| D | ASN210 |
| D | PRO297 |
| site_id | ASP |
| Number of Residues | 1 |
| Details | CATALYTIC RESIDUES IN THE MATURE ENZYME. |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE31-VAL42 | |
| A | CYS211-VAL222 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| A | THR217 | |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | ASP214 | |
| B | SER37 | |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP34 | |
| C | ASP214 | |
| C | SER37 | |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP34 | |
| D | ASP214 | |
| D | SER37 | |
| site_id | CSA13 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | THR35 | |
| A | ASP214 | |
| A | THR217 | |
| site_id | CSA14 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | THR35 | |
| B | ASP214 | |
| B | THR217 | |
| site_id | CSA15 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP34 | |
| C | THR35 | |
| C | ASP214 | |
| C | THR217 | |
| site_id | CSA16 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP34 | |
| D | THR35 | |
| D | ASP214 | |
| D | THR217 | |
| site_id | CSA17 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| site_id | CSA18 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | ASP214 | |
| site_id | CSA19 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP34 | |
| C | ASP214 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | ASP214 | |
| B | SER37 | |
| B | THR217 | |
| site_id | CSA20 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP34 | |
| D | ASP214 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP34 | |
| C | ASP214 | |
| C | SER37 | |
| C | THR217 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP34 | |
| D | ASP214 | |
| D | SER37 | |
| D | THR217 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER215 | |
| A | ASP34 | |
| A | THR35 | |
| A | ASP214 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | SER215 | |
| B | ASP34 | |
| B | THR35 | |
| B | ASP214 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | SER215 | |
| C | ASP34 | |
| C | THR35 | |
| C | ASP214 | |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | SER215 | |
| D | ASP34 | |
| D | THR35 | |
| D | ASP214 | |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
