1PCP

SOLUTION STRUCTURE OF A TREFOIL-MOTIF-CONTAINING CELL GROWTH FACTOR, PORCINE SPASMOLYTIC PROTEIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0030277	biological_process	maintenance of gastrointestinal epithelium
A	0031723	molecular_function	CXCR4 chemokine receptor binding
A	0060455	biological_process	negative regulation of gastric acid secretion
A	0070098	biological_process	chemokine-mediated signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00025
Number of Residues	21
Details	P_TREFOIL_1 P-type 'Trefoil' domain signature. RvnCgFpgi.TsdqCftsgCCF

Chain	Residue	Details
A	ARG16-PHE36
A	ARG65-PHE85

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	Domain: {"description":"P-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00779","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	43
Details	Domain: {"description":"P-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00779","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Pyrrolidone carboxylic acid","evidences":[{"source":"PubMed","id":"2857575","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---