1PAF
THE 2.5 ANGSTROMS STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0030598 | molecular_function | rRNA N-glycosylase activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0051607 | biological_process | defense response to virus |
| A | 0090729 | molecular_function | toxin activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017148 | biological_process | negative regulation of translation |
| B | 0030598 | molecular_function | rRNA N-glycosylase activity |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0051607 | biological_process | defense response to virus |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PROSITE/UniProt
| site_id | PS00275 |
| Number of Residues | 17 |
| Details | SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMVsEAARFKyIEnqV |
| Chain | Residue | Details |
| A | ILE171-VAL187 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P84531 |
| Chain | Residue | Details |
| A | TYR72 | |
| A | TYR123 | |
| A | GLU176 | |
| A | ARG179 | |
| B | TYR72 | |
| B | TYR123 | |
| B | GLU176 | |
| B | ARG179 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0000269|PubMed:10595542, ECO:0000269|PubMed:8411176, ECO:0007744|PDB:1D6A, ECO:0007744|PDB:1PAG, ECO:0007744|PDB:1QCI, ECO:0007744|PDB:1QCJ |
| Chain | Residue | Details |
| A | VAL73 | |
| B | VAL73 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0000269|PubMed:10595542, ECO:0000269|PubMed:8411176, ECO:0007744|PDB:1D6A, ECO:0007744|PDB:1PAG, ECO:0007744|PDB:1QCJ |
| Chain | Residue | Details |
| A | SER121 | |
| B | SER121 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0007744|PDB:1QCJ |
| Chain | Residue | Details |
| A | SER175 | |
| B | SER175 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0000269|PubMed:10595542, ECO:0000269|PubMed:8411176, ECO:0007744|PDB:1D6A, ECO:0007744|PDB:1PAG, ECO:0007744|PDB:1QCI |
| Chain | Residue | Details |
| A | ARG179 | |
| B | ARG179 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1abr |
| Chain | Residue | Details |
| A | ARG179 | |
| A | GLU176 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1abr |
| Chain | Residue | Details |
| B | ARG179 | |
| B | GLU176 |
