Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CSN A 737 |
| Chain | Residue |
| A | PHE67 |
| A | GLY246 |
| A | ARG247 |
| A | ILE281 |
| A | GLN284 |
| A | HOH810 |
| A | ILE70 |
| A | ASP194 |
| A | GLN195 |
| A | CYS241 |
| A | ARG242 |
| A | ALA243 |
| A | GLY244 |
| A | VAL245 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCraGvgRTA |
| Chain | Residue | Details |
| A | ILE239-ALA249 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Phosphocysteine intermediate |
| Chain | Residue | Details |
| A | CYS241 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 47 |
| Chain | Residue | Details |
| A | GLU128 | steric role |
| A | TRP192 | steric role |
| A | ASP194 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | HIS240 | electrostatic stabiliser, hydrogen bond donor |
| A | CYS241 | nucleofuge, nucleophile |
| A | ARG247 | electrostatic stabiliser, hydrogen bond donor |
| A | THR248 | electrostatic stabiliser, hydrogen bond donor |
