1P7J

Crystal structure of engrailed homeodomain mutant K52E

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription
C	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
C	0003677	molecular_function	DNA binding
C	0006355	biological_process	regulation of DNA-templated transcription
D	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
D	0003677	molecular_function	DNA binding
D	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NHE A 500

Chain	Residue
A	TYR25
A	GLU37
A	HOH519
A	HOH548
A	HOH549
A	HOH550
B	GLU11
B	LEU38

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Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LSseLgLNeaQIKIWFqNerakiK

Chain	Residue	Details
A	LEU34-LYS57

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