1P5H
Crystal structure of Formyl-CoA Transferase (apoenzyme) from Oxalobacter formigenes
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0033608 | molecular_function | formyl-CoA transferase activity |
| A | 0033611 | biological_process | oxalate catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0033608 | molecular_function | formyl-CoA transferase activity |
| B | 0033611 | biological_process | oxalate catabolic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00742, ECO:0000269|PubMed:15213226 |
| Chain | Residue | Details |
| A | SER170 | |
| B | SER170 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | VAL16 | |
| B | GLY261 | |
| A | ASP73 | |
| A | PHE97 | |
| A | VAL138 | |
| A | GLY261 | |
| B | VAL16 | |
| B | ASP73 | |
| B | PHE97 | |
| B | VAL138 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00742, ECO:0000269|PubMed:12839984, ECO:0000269|PubMed:15213226, ECO:0000269|PubMed:18162462 |
| Chain | Residue | Details |
| A | ARG39 | |
| A | MET105 | |
| B | ARG39 | |
| B | MET105 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1xvt |
| Chain | Residue | Details |
| A | ASP169 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1xvt |
| Chain | Residue | Details |
| B | ASP169 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 155 |
| Chain | Residue | Details |
| A | GLN17 | electrostatic stabiliser, hydrogen bond donor |
| A | GLU140 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP169 | covalently attached, electrofuge, electrophile, nucleofuge, nucleophile |
| A | GLY260 | electrostatic stabiliser, hydrogen bond acceptor |
| A | GLY261 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 155 |
| Chain | Residue | Details |
| B | GLN17 | electrostatic stabiliser, hydrogen bond donor |
| B | GLU140 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP169 | covalently attached, electrofuge, electrophile, nucleofuge, nucleophile |
| B | GLY260 | electrostatic stabiliser, hydrogen bond acceptor |
| B | GLY261 | electrostatic stabiliser, hydrogen bond donor |
