1P4V

CRYSTAL STRUCTURE OF THE GLYCOSYLASPARAGINASE PRECURSOR D151N MUTANT WITH GLYCINE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003948	molecular_function	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity
A	0004067	molecular_function	asparaginase activity
A	0005737	cellular_component	cytoplasm
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008798	molecular_function	beta-aspartyl-peptidase activity
A	0016787	molecular_function	hydrolase activity
A	0042597	cellular_component	periplasmic space
C	0003948	molecular_function	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity
C	0004067	molecular_function	asparaginase activity
C	0005737	cellular_component	cytoplasm
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008798	molecular_function	beta-aspartyl-peptidase activity
C	0016787	molecular_function	hydrolase activity
C	0042597	cellular_component	periplasmic space

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GLY A 296

Chain	Residue
A	THR152
A	GLY172
A	MET173
A	ARG180
A	ASP183
A	SER184
A	GLY204
A	GLY206
A	HOH301

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GLY C 596

Chain	Residue
C	HOH7
C	HOH10
C	THR452
C	GLY472
C	MET473
C	ARG480
C	ASP483
C	SER484
C	GLY504
C	GLY506

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:10490104, ECO:0000269|PubMed:17157318, ECO:0000269|PubMed:20800597, ECO:0000269|PubMed:9685368

Chain	Residue	Details
A	THR152
C	THR452

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	ARG180
A	THR203
C	ARG480
C	THR503

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	Annotated By Reference To The Literature 1apy

Chain	Residue	Details
A	GLY204
A	THR152
A	THR170
A	SER50
A	THR203

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site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 1apy

Chain	Residue	Details
C	SER350
C	THR452
C	GLY504
C	THR503
C	THR470

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