1P4S

Solution structure of Mycobacterium tuberculosis adenylate kinase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004017	molecular_function	AMP kinase activity
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006144	biological_process	purine nucleobase metabolic process
A	0009123	biological_process	nucleoside monophosphate metabolic process
A	0009132	biological_process	nucleoside diphosphate metabolic process
A	0009141	biological_process	nucleoside triphosphate metabolic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0019205	molecular_function	nucleobase-containing compound kinase activity
A	0044209	biological_process	AMP salvage
A	0046940	biological_process	nucleoside monophosphate phosphorylation

Functional Information from PROSITE/UniProt

site_id	PS00113
Number of Residues	12
Details	ADENYLATE_KINASE Adenylate kinase signature. FILDGYPRsveQ

Chain	Residue	Details
A	PHE81-GLN92

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	29
Details	Region: {"description":"NMP","evidences":[{"source":"HAMAP-Rule","id":"MF_00235","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14705932","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	6
Details	Region: {"description":"LID","evidences":[{"source":"HAMAP-Rule","id":"MF_00235","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14705932","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	17
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00235","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16672241","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	2
Details	Cross-link: {"description":"Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)","evidences":[{"source":"PubMed","id":"20066036","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	6
Details	Annotated By Reference To The Literature 1zio