1P4A
Crystal Structure of the PurR complexed with cPRPP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0045982 | biological_process | negative regulation of purine nucleobase metabolic process |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0045982 | biological_process | negative regulation of purine nucleobase metabolic process |
| C | 0003677 | molecular_function | DNA binding |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| C | 0045982 | biological_process | negative regulation of purine nucleobase metabolic process |
| D | 0003677 | molecular_function | DNA binding |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| D | 0045982 | biological_process | negative regulation of purine nucleobase metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PCP A 604 |
| Chain | Residue |
| A | ALA138 |
| A | GLY209 |
| A | GLY210 |
| A | THR211 |
| A | HOH620 |
| A | HOH694 |
| B | ARG160 |
| A | THR139 |
| A | LYS140 |
| A | GLY178 |
| A | ASP203 |
| A | ASP204 |
| A | PHE205 |
| A | LYS207 |
| A | ALA208 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE PCP B 605 |
| Chain | Residue |
| A | ARG160 |
| B | VAL137 |
| B | ALA138 |
| B | THR139 |
| B | LYS140 |
| B | GLY141 |
| B | LYS161 |
| B | GLY178 |
| B | ASP203 |
| B | ASP204 |
| B | PHE205 |
| B | MET206 |
| B | LYS207 |
| B | ALA208 |
| B | GLY209 |
| B | GLY210 |
| B | THR211 |
| B | HOH609 |
| B | HOH610 |
| B | HOH674 |
| B | HOH714 |
| B | HOH760 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE PCP C 606 |
| Chain | Residue |
| C | ALA138 |
| C | THR139 |
| C | LYS140 |
| C | LYS161 |
| C | SER177 |
| C | GLY178 |
| C | ASP203 |
| C | ASP204 |
| C | PHE205 |
| C | MET206 |
| C | LYS207 |
| C | ALA208 |
| C | GLY209 |
| C | GLY210 |
| C | THR211 |
| C | HOH608 |
| C | HOH652 |
| C | HOH659 |
| C | HOH671 |
| C | HOH691 |
| C | HOH745 |
| D | ARG160 |
| D | HOH625 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PCP D 607 |
| Chain | Residue |
| C | ARG160 |
| D | ALA138 |
| D | THR139 |
| D | LYS140 |
| D | SER177 |
| D | GLY178 |
| D | ASP203 |
| D | ASP204 |
| D | PHE205 |
| D | MET206 |
| D | LYS207 |
| D | ALA208 |
| D | GLY209 |
| D | GLY210 |
| D | THR211 |
| D | HOH619 |
| D | HOH636 |
| D | HOH685 |
| D | HOH725 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oro |
| Chain | Residue | Details |
| B | SER169 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oro |
| Chain | Residue | Details |
| C | SER169 |
