1P2C

crystal structure analysis of an anti-lysozyme antibody

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0030183	biological_process	B cell differentiation
C	0003796	molecular_function	lysozyme activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0016231	molecular_function	beta-N-acetylglucosaminidase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0031640	biological_process	killing of cells of another organism
C	0042742	biological_process	defense response to bacterium
C	0042802	molecular_function	identical protein binding
C	0050829	biological_process	defense response to Gram-negative bacterium
C	0050830	biological_process	defense response to Gram-positive bacterium
C	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
D	0005576	cellular_component	extracellular region
D	0005886	cellular_component	plasma membrane
D	0030183	biological_process	B cell differentiation
F	0003796	molecular_function	lysozyme activity
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0016231	molecular_function	beta-N-acetylglucosaminidase activity
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0016998	biological_process	cell wall macromolecule catabolic process
F	0031640	biological_process	killing of cells of another organism
F	0042742	biological_process	defense response to bacterium
F	0042802	molecular_function	identical protein binding
F	0050829	biological_process	defense response to Gram-negative bacterium
F	0050830	biological_process	defense response to Gram-positive bacterium
F	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
C	CYS676-CYS694

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site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
A	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE:

Chain	Residue	Details
C	GLU635
C	ASP652
F	GLU1535
F	ASP1552

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
C	ASP701
F	ASP1601

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
C	GLU635
C	ASP652

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
F	ASP1552
F	GLU1535

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site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
C	GLU635	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	ASN646
C	ASP648
C	SER650
C	ASP652	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
C	ASN659

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site_id	MCSA2
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
F	GLU1535	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
F	ASN1546
F	ASP1548
F	SER1550
F	ASP1552	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
F	ASN1559

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