Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1P1F

Crystal structure of apo 1L-myo-inositol 1-phosphate synthase

Functional Information from GO Data
ChainGOidnamespacecontents
A0004512molecular_functioninositol-3-phosphate synthase activity
A0005737cellular_componentcytoplasm
A0006021biological_processinositol biosynthetic process
A0008654biological_processphospholipid biosynthetic process
A0016853molecular_functionisomerase activity
B0004512molecular_functioninositol-3-phosphate synthase activity
B0005737cellular_componentcytoplasm
B0006021biological_processinositol biosynthetic process
B0008654biological_processphospholipid biosynthetic process
B0016853molecular_functionisomerase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12836703, ECO:0007744|PDB:1JKF, ECO:0007744|PDB:1LA2
ChainResidueDetails
AGLY74
BGLY74

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:12836703, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1JKF, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1I, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1RM0
ChainResidueDetails
AGLY75
BGLY75

site_idSWS_FT_FI3
Number of Residues10
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:12836703, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1JKF, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1I, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
AASN76
BTHR247
AASN77
AASP148
AALA245
ATHR247
BASN76
BASN77
BASP148
BALA245

site_idSWS_FT_FI4
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1JKF, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1I, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
ASER184
BSER184

site_idSWS_FT_FI5
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:12836703, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1I, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
AILE185
AARG198
BILE185
BARG198

site_idSWS_FT_FI6
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0007744|PDB:1JKF
ChainResidueDetails
AGLN195
AASP196
ALEU321
AGLY409
BGLN195
BASP196
BLEU321
BGLY409

site_idSWS_FT_FI7
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:12836703, ECO:0007744|PDB:1LA2
ChainResidueDetails
ATHR244
BTHR244

site_idSWS_FT_FI8
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1JKF, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1I, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
AASN246
BASN246

site_idSWS_FT_FI9
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1P1H
ChainResidueDetails
AGLY295
BGLY295

site_idSWS_FT_FI10
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:12836703, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1I, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
ASER296
AASN355
BSER296
BASN355

site_idSWS_FT_FI11
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0007744|PDB:1JKF, ECO:0007744|PDB:1P1H
ChainResidueDetails
AASP320
BASP320

site_idSWS_FT_FI12
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0007744|PDB:1JKF, ECO:0007744|PDB:1P1J
ChainResidueDetails
ASER323
BSER323

site_idSWS_FT_FI13
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:12836703, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H
ChainResidueDetails
AASN354
BASN354

site_idSWS_FT_FI14
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:12836703, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
AASP356
BASP356

site_idSWS_FT_FI15
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
ALYS369
BLYS369

site_idSWS_FT_FI16
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0007744|PDB:1JKI
ChainResidueDetails
AASP410
BASP410

site_idSWS_FT_FI17
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:12832758, ECO:0000269|PubMed:12836703, ECO:0000269|PubMed:14684747, ECO:0007744|PDB:1LA2, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1J, ECO:0007744|PDB:1P1K, ECO:0007744|PDB:1RM0
ChainResidueDetails
AASP438
BASP438

site_idSWS_FT_FI18
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11779862, ECO:0000269|PubMed:12832758, ECO:0007744|PDB:1JKI, ECO:0007744|PDB:1P1H, ECO:0007744|PDB:1P1K
ChainResidueDetails
ASER439
BSER439

site_idSWS_FT_FI19
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000269|PubMed:23902760
ChainResidueDetails
ATHR48
BTHR48

site_idSWS_FT_FI20
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:23902760
ChainResidueDetails
ASER177
ASER184
ASER296
BSER177
BSER184
BSER296

site_idSWS_FT_FI21
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
ASER368
BSER368

site_idSWS_FT_FI22
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000305|PubMed:23902760
ChainResidueDetails
ASER374
BSER374

Catalytic Information from CSA
site_idMCSA1
Number of Residues4
DetailsM-CSA 331
ChainResidueDetails
AASP320electrostatic stabiliser, hydrogen bond acceptor
ALYS369activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
ALYS412activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
ALYS489electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_idMCSA2
Number of Residues4
DetailsM-CSA 331
ChainResidueDetails
BASP320electrostatic stabiliser, hydrogen bond acceptor
BLYS369activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
BLYS412activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
BLYS489electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

222415

PDB entries from 2024-07-10

PDB statisticsPDBj update infoContact PDBjnumon