Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1 |
| Chain | Residue |
| A | ALA15 |
| A | ASN15 |
| A | ARG230 |
| A | PRO233 |
| A | HOH271 |
| A | HOH282 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR CHAIN P OF METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR |
| Chain | Residue |
| A | MET192 |
| A | GLY192 |
| A | ARG192 |
| A | GLY193 |
| A | ASP194 |
| A | SER195 |
| A | SER214 |
| A | GLY215 |
| A | GLY216 |
| A | VAL217 |
| P | HOH90 |
| P | HOH103 |
| A | HIS57 |
| A | ARG125 |
| A | TYR171 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWI |
| Chain | Residue | Details |
| A | CYS191-ILE200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ssx |
| Chain | Residue | Details |
| A | ASP102 | |
| A | SER195 | |
| A | GLY193 | |
| A | HIS57 | |
| A | SER214 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ssx |
| Chain | Residue | Details |
| A | ASP102 | |
| A | SER195 | |
| A | GLY193 | |
| A | HIS57 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| A | HIS57 | proton acceptor, proton donor |
| A | ASP102 | electrostatic stabiliser |
| A | GLY193 | electrostatic stabiliser |
| A | SER195 | electrostatic stabiliser |
| A | SER214 | electrostatic stabiliser |
