Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 1 |
Chain | Residue |
A | ALA15 |
A | ASN15 |
A | ARG230 |
A | PRO233 |
A | HOH282 |
A | HOH329 |
A | HOH356 |
A | HOH372 |
site_id | AC2 |
Number of Residues | 14 |
Details | BINDING SITE FOR CHAIN P OF METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID |
Chain | Residue |
A | HIS57 |
A | ARG125 |
A | TYR171 |
A | GLU174 |
A | ARG192 |
A | SER195 |
A | SER214 |
A | GLY215 |
A | GLY216 |
A | VAL217 |
A | HOH262 |
A | HOH361 |
P | HOH90 |
A | CYS42 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
Chain | Residue | Details |
A | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWI |
Chain | Residue | Details |
A | CYS191-ILE200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system => ECO:0000250 |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1ssx |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | GLY193 | |
A | HIS57 | |
A | SER214 | |
site_id | CSA2 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1ssx |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | GLY193 | |
A | HIS57 | |
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 609 |
Chain | Residue | Details |
A | HIS57 | proton acceptor, proton donor |
A | ASP102 | electrostatic stabiliser |
A | GLY193 | electrostatic stabiliser |
A | SER195 | electrostatic stabiliser |
A | SER214 | electrostatic stabiliser |