1OZP
Crystal Structure of Rv0819 from Mycobacterium tuberculosis MshD-Mycothiol Synthase Acetyl-Coenzyme A Complex.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008999 | molecular_function | protein-N-terminal-alanine acetyltransferase activity |
| A | 0010125 | biological_process | mycothiol biosynthetic process |
| A | 0010126 | biological_process | mycothiol metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0035447 | molecular_function | mycothiol synthase activity |
| A | 0051701 | biological_process | biological process involved in interaction with host |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0071468 | biological_process | cellular response to acidic pH |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE ACO A 600 |
| Chain | Residue |
| A | ASP29 |
| A | ILE91 |
| A | GLY92 |
| A | THR93 |
| A | ARG106 |
| A | TRP110 |
| A | PRO117 |
| A | ALA118 |
| A | ALA120 |
| A | THR121 |
| A | HOH609 |
| A | PRO33 |
| A | HOH611 |
| A | HOH647 |
| A | HOH648 |
| A | HOH661 |
| A | HOH727 |
| A | HOH779 |
| A | HOH839 |
| A | HOH882 |
| A | HOH908 |
| A | HOH970 |
| A | LEU80 |
| A | VAL81 |
| A | VAL82 |
| A | ARG87 |
| A | ARG88 |
| A | ARG89 |
| A | GLY90 |
| site_id | AC2 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE ACO A 601 |
| Chain | Residue |
| A | ALA158 |
| A | GLY159 |
| A | THR160 |
| A | SER161 |
| A | ALA173 |
| A | PHE174 |
| A | VAL235 |
| A | VAL237 |
| A | LEU238 |
| A | GLY239 |
| A | VAL240 |
| A | GLN245 |
| A | ARG246 |
| A | ARG247 |
| A | GLY248 |
| A | GLY250 |
| A | GLN251 |
| A | TYR282 |
| A | ASN287 |
| A | ALA289 |
| A | ALA290 |
| A | ARG292 |
| A | THR293 |
| A | TYR294 |
| A | SER296 |
| A | HOH602 |
| A | HOH604 |
| A | HOH607 |
| A | HOH614 |
| A | HOH623 |
| A | HOH630 |
| A | HOH635 |
| A | HOH640 |
| A | HOH660 |
| A | HOH664 |
| A | HOH732 |
| A | HOH734 |
| A | HOH946 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16326705","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {} |
| Chain | Residue | Details |
