Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1OXU

Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006826	biological_process	iron ion transport
A	0015408	molecular_function	ABC-type ferric iron transporter activity
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0022857	molecular_function	transmembrane transporter activity
A	0034755	biological_process	iron ion transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0098655	biological_process	monoatomic cation transmembrane transport
A	1902495	cellular_component	transmembrane transporter complex
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006826	biological_process	iron ion transport
B	0015408	molecular_function	ABC-type ferric iron transporter activity
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0022857	molecular_function	transmembrane transporter activity
B	0034755	biological_process	iron ion transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0098655	biological_process	monoatomic cation transmembrane transport
B	1902495	cellular_component	transmembrane transporter complex
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006826	biological_process	iron ion transport
C	0015408	molecular_function	ABC-type ferric iron transporter activity
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0022857	molecular_function	transmembrane transporter activity
C	0034755	biological_process	iron ion transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0098655	biological_process	monoatomic cation transmembrane transport
C	1902495	cellular_component	transmembrane transporter complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 1501

Chain	Residue
C	THR45
C	ADP1487
C	HOH2829
C	HOH2911
C	HOH3073
C	HOH3074

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1502

Chain	Residue
A	HOH3064
A	HOH3093
A	HOH3094
A	THR45
A	ADP1486
A	HOH3014

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 1503

Chain	Residue
B	THR45
B	ADP1488
B	HOH2847
B	HOH2865
B	HOH2915
B	HOH2950

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2001

Chain	Residue
C	LYS17
C	LEU283

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD B 2002

Chain	Residue
B	LYS17
B	LEU283
B	SER328

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 2003

Chain	Residue
A	LYS17
A	LEU283
A	SER328

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD C 2004

Chain	Residue
C	ARG67
C	ARG82
C	HOH2833

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 2006

Chain	Residue
A	ARG67
A	ARG82

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2007

Chain	Residue
A	GLN147

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2008

Chain	Residue
C	GLN147
C	LEU151

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2009

Chain	Residue
A	PHE88

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 2010

Chain	Residue
A	ILE26
B	HOH2888

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2011

Chain	Residue
A	ILE304

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 2012

Chain	Residue
B	SER234

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD C 2013

Chain	Residue
C	PHE88

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2014

Chain	Residue
C	ASN135
C	HOH2929

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 2015

Chain	Residue
B	MET86

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2016

Chain	Residue
A	LYS184

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD B 2017

Chain	Residue
B	ARG67
B	ARG82
B	LYS83
B	IOD2019

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2018

Chain	Residue
C	TYR94
C	ASN96

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 2019

Chain	Residue
B	ARG67
B	IOD2017

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2020

Chain	Residue
C	VAL303
C	ILE304

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 2021

Chain	Residue
B	ILE127
B	ARG189

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2023

Chain	Residue
A	MET86

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 2339

Chain	Residue
A	PHE105
A	HOH3193

site_id	CC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 2386

Chain	Residue
B	SER328

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 2387

Chain	Residue
A	GLY144
A	HOH3151

site_id	DC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2438

Chain	Residue
C	SER234
C	GLN236

site_id	DC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2536

Chain	Residue
C	ARG148
C	HOH3002

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2541

Chain	Residue
C	HOH2882
C	HOH3068

site_id	DC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD C 2682

Chain	Residue
C	HOH3095

site_id	DC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2683

Chain	Residue
A	SER234

site_id	DC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2816

Chain	Residue
A	GLN146

site_id	DC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD C 2823

Chain	Residue
C	LYS15

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2828

Chain	Residue
A	IOD2845

site_id	DC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 2831

Chain	Residue
B	LYS15

site_id	EC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2832

Chain	Residue
A	LYS15

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 2845

Chain	Residue
A	IOD2828
A	HOH3222

site_id	EC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 2986

Chain	Residue
A	HOH3242

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD C 2049

Chain	Residue
C	HOH3092

site_id	EC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 2153

Chain	Residue
A	TYR94
A	ASN96

site_id	EC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 2037

Chain	Residue
B	VAL303
B	ILE304

site_id	EC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2233

Chain	Residue
C	PRO201
C	ALA202

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD C 2239

Chain	Residue
C	HOH2927

site_id	EC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 2288

Chain	Residue
A	VAL12
A	HOH3116

site_id	FC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 2337

Chain	Residue
B	HOH2934

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2253

Chain	Residue
C	PHE205
C	ILE241

site_id	FC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 2198

Chain	Residue
B	GLU61

site_id	FC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD B 2218

Chain	Residue
B	ARG33
B	SER188
B	HOH2992

site_id	FC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD C 2237

Chain	Residue
C	LYS14
C	ASP329

site_id	FC6
Number of Residues	22
Details	BINDING SITE FOR RESIDUE ADP A 1486

Chain	Residue
A	SER40
A	GLY41
A	ALA42
A	GLY43
A	LYS44
A	THR45
A	THR46
A	MG1502
A	HOH2998
A	HOH3014
A	HOH3064
A	HOH3094
A	HOH3098
A	HOH3119
A	HOH3143
A	HOH3163
A	HOH3168
A	HOH3176
A	HOH3179
A	HOH3208
A	PHE13
A	ALA20

site_id	FC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE ADP C 1487

Chain	Residue
C	PHE13
C	ALA20
C	SER40
C	GLY41
C	ALA42
C	GLY43
C	LYS44
C	THR45
C	THR46
C	MG1501
C	HOH2911
C	HOH2936
C	HOH2953
C	HOH2959
C	HOH2968
C	HOH3021
C	HOH3028
C	HOH3047
C	HOH3074
C	HOH3080

site_id	FC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP B 1488

Chain	Residue
B	PHE13
B	ALA20
B	GLY41
B	ALA42
B	GLY43
B	LYS44
B	THR45
B	THR46
B	MG1503
B	HOH2915
B	HOH2943
B	HOH2950
B	HOH2986
B	HOH2989
B	HOH3005
B	HOH3029

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQQQRVALARAL

Chain	Residue	Details
A	LEU141-LEU155

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	711
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12823973","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)