Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE I3P A 1601 |
| Chain | Residue |
| A | LYS1045 |
| A | HOH6118 |
| B | LYS1059 |
| A | ARG1076 |
| A | HIS1081 |
| A | LYS1082 |
| A | ARG1124 |
| A | LYS1142 |
| A | HOH6002 |
| A | HOH6031 |
| A | HOH6034 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE I3P B 1602 |
| Chain | Residue |
| A | LYS1059 |
| A | LYS1173 |
| B | LYS1045 |
| B | ARG1076 |
| B | HIS1081 |
| B | LYS1082 |
| B | ARG1124 |
| B | HOH6035 |
| B | HOH6087 |
| B | HOH6226 |
Functional Information from PROSITE/UniProt
| site_id | PS00320 |
| Number of Residues | 8 |
| Details | APP_INTRA Amyloid precursor protein (APP) intracellular domain signature. GYENPTYK |
| Chain | Residue | Details |
| C | GLY1502-LYS1509 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Motif: {"description":"YENPXY motif; contains endocytosis signal","evidences":[{"source":"UniProtKB","id":"P05067","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by ABL1","evidences":[{"source":"UniProtKB","id":"P12023","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22847417","evidenceCode":"ECO:0000269"}]} |
