1OOE
Structural Genomics of Caenorhabditis elegans : Dihydropteridine reductase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004155 | molecular_function | 6,7-dihydropteridine reductase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| A | 0070402 | molecular_function | NADPH binding |
| A | 0070404 | molecular_function | NADH binding |
| B | 0004155 | molecular_function | 6,7-dihydropteridine reductase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042558 | biological_process | pteridine-containing compound metabolic process |
| B | 0070402 | molecular_function | NADPH binding |
| B | 0070404 | molecular_function | NADH binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MES A 2001 |
| Chain | Residue |
| A | SER66 |
| A | HIS204 |
| A | LYS207 |
| A | TRP208 |
| A | SER214 |
| A | PRO216 |
| A | HOH1043 |
| A | HOH1516 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MES B 2002 |
| Chain | Residue |
| B | HIS204 |
| B | LYS207 |
| B | TRP208 |
| B | SER213 |
| B | SER214 |
| B | PRO216 |
| B | HOH1162 |
| B | HOH1522 |
| B | HOH1588 |
| B | LEU35 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. AaaamgptpsMigYGMAKAAVhHLTsSLA |
| Chain | Residue | Details |
| A | ALA130-ALA158 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| A | ASN183 | |
| A | TYR143 | |
| A | LYS147 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| B | ASN183 | |
| B | TYR143 | |
| B | LYS147 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| A | MET140 | |
| A | LYS147 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| B | MET140 | |
| B | LYS147 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| A | TYR143 | |
| A | LYS147 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| B | TYR143 | |
| B | LYS147 |
