1ON6
Crystal structure of mouse alpha-1,4-N-acetylhexosaminotransferase (EXTL2) in complex with UDPGlcNAc
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 600 |
| Chain | Residue |
| A | ASP153 |
| A | UD1401 |
| A | HOH656 |
| A | HOH690 |
| A | HOH691 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 601 |
| Chain | Residue |
| B | HOH684 |
| B | ASP153 |
| B | UD1400 |
| B | HOH654 |
| B | HOH683 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE UD1 B 400 |
| Chain | Residue |
| B | GLN72 |
| B | THR73 |
| B | TYR74 |
| B | ARG76 |
| B | ASN101 |
| B | ASN130 |
| B | MET132 |
| B | ARG135 |
| B | ASP151 |
| B | ASP152 |
| B | ASP153 |
| B | LEU213 |
| B | ASN243 |
| B | ASP245 |
| B | ASP246 |
| B | HIS289 |
| B | ARG293 |
| B | MN601 |
| B | HOH602 |
| B | HOH642 |
| B | HOH654 |
| B | HOH673 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE UD1 A 401 |
| Chain | Residue |
| A | GLN72 |
| A | THR73 |
| A | TYR74 |
| A | ARG76 |
| A | ASN101 |
| A | ASN130 |
| A | MET132 |
| A | ARG135 |
| A | ASP151 |
| A | ASP152 |
| A | ASP153 |
| A | LEU213 |
| A | GLY215 |
| A | ASP245 |
| A | ASP246 |
| A | HIS289 |
| A | ARG293 |
| A | MN600 |
| A | HOH617 |
| A | HOH630 |
| A | HOH690 |
| A | HOH691 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 501 |
| Chain | Residue |
| A | PHE171 |
| A | GLN174 |
| A | PRO260 |
| A | ILE263 |
| A | HOH631 |
| B | GLN170 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 502 |
| Chain | Residue |
| A | GLN170 |
| A | PHE171 |
| B | PHE171 |
| B | GLN174 |
| B | PRO260 |
| B | ILE314 |
| B | HOH633 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"12562774","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12562774","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ON6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ON8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12562774","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ON6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
