1OMX

Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0016757	molecular_function	glycosyltransferase activity
B	0016020	cellular_component	membrane
B	0016757	molecular_function	glycosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 401

Chain	Residue
A	PHE171
A	GLN174
A	PRO260
A	ILE314
A	HOH432

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 402

Chain	Residue
B	HOH417
B	PHE171
B	GLN174
B	PRO260
B	ILE263

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 403

Chain	Residue
A	LYS222
A	TYR223

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	THR38-SER58
B	THR38-SER58

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site_id	SWS_FT_FI2
Number of Residues	40
Details	TRANSMEM: Helical; Signal-anchor for type II membrane protein => ECO:0000255

Chain	Residue	Details
A	PRO59-LEU79
B	PRO59-LEU79

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site_id	SWS_FT_FI3
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:12562774

Chain	Residue	Details
A	MET283
B	MET283

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site_id	SWS_FT_FI4
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:12562774, ECO:0007744|PDB:1ON6, ECO:0007744|PDB:1ON8

Chain	Residue	Details
A	GLU109
B	GLY189
A	ASN113
A	VAL138
A	ILE167
A	GLY189
B	GLU109
B	ASN113
B	VAL138
B	ILE167

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site_id	SWS_FT_FI5
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:12562774, ECO:0007744|PDB:1ON6

Chain	Residue	Details
A	PRO172
B	GLY282
B	MET283
B	MET330
A	SER188
A	ILE190
A	GLY282
A	MET283
A	MET330
B	PRO172
B	SER188
B	ILE190

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site_id	SWS_FT_FI6
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	TRP112
B	TRP112

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