Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0005509 | molecular_function | calcium ion binding |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0031012 | cellular_component | extracellular matrix |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 600 |
Chain | Residue |
A | HIS169 |
A | HIS173 |
A | HIS179 |
A | HOH1459 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 700 |
Chain | Residue |
A | ASP114 |
A | ASP49 |
A | ASN51 |
A | ASP53 |
A | VAL55 |
A | ASN57 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 701 |
Chain | Residue |
A | ARG250 |
A | ASP252 |
A | THR254 |
A | ASP282 |
A | GLY284 |
A | ASP287 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 702 |
Chain | Residue |
A | GLY285 |
A | ASP287 |
A | THR324 |
A | GLU326 |
A | HOH1057 |
A | HOH1463 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 703 |
Chain | Residue |
A | GLY331 |
A | GLY333 |
A | ASP335 |
A | GLY348 |
A | ALA350 |
A | ASP353 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 704 |
Chain | Residue |
A | GLY349 |
A | GLY351 |
A | ASP353 |
A | GLY366 |
A | THR368 |
A | ASP371 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 705 |
Chain | Residue |
A | ASN340 |
A | ALA342 |
A | ASN344 |
A | GLY357 |
A | GLY359 |
A | ASP362 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 706 |
Chain | Residue |
A | GLY358 |
A | GLY360 |
A | ASP362 |
A | ASP380 |
A | ASP387 |
A | HOH1344 |
site_id | AC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 707 |
Chain | Residue |
A | GLY367 |
A | GLY369 |
A | ASP371 |
A | GLN393 |
A | ASP397 |
A | HOH1076 |
site_id | BC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 500 |
Chain | Residue |
A | ARG139 |
A | TRP210 |
A | SER211 |
A | ASN214 |
A | HOH1035 |
A | HOH1181 |
A | HOH1267 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TLTHEIGHTL |
Chain | Residue | Details |
A | THR166-LEU175 | |
site_id | PS00330 |
Number of Residues | 19 |
Details | HEMOLYSIN_CALCIUM Hemolysin-type calcium-binding region signature. DiIygggGaDvLwGGtgsD |
Chain | Residue | Details |
A | ASP353-ASP371 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1qib |
Chain | Residue | Details |
A | GLU170 | |