1OLP
Alpha Toxin from Clostridium Absonum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004629 | molecular_function | phospholipase C activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0034480 | molecular_function | phosphatidylcholine phospholipase C activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090729 | molecular_function | toxin activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004629 | molecular_function | phospholipase C activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0034480 | molecular_function | phosphatidylcholine phospholipase C activity |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0090729 | molecular_function | toxin activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004629 | molecular_function | phospholipase C activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0034480 | molecular_function | phosphatidylcholine phospholipase C activity |
| C | 0035821 | biological_process | modulation of process of another organism |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0090729 | molecular_function | toxin activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004629 | molecular_function | phospholipase C activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| D | 0031640 | biological_process | killing of cells of another organism |
| D | 0034480 | molecular_function | phosphatidylcholine phospholipase C activity |
| D | 0035821 | biological_process | modulation of process of another organism |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 1371 |
| Chain | Residue |
| A | ASP269 |
| A | GLY271 |
| A | GLY337 |
| A | HOH2101 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 1372 |
| Chain | Residue |
| A | ASP293 |
| A | ASN294 |
| A | GLY296 |
| A | ASP298 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1373 |
| Chain | Residue |
| A | HIS11 |
| A | ASP130 |
| A | ZN1375 |
| A | TRP1 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 1374 |
| Chain | Residue |
| A | HIS136 |
| A | HIS148 |
| A | GLU152 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1375 |
| Chain | Residue |
| A | ASP56 |
| A | HIS68 |
| A | HIS126 |
| A | ASP130 |
| A | ZN1373 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 1371 |
| Chain | Residue |
| B | ASP293 |
| B | ASN294 |
| B | GLY296 |
| B | ASP298 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 1372 |
| Chain | Residue |
| B | ASP269 |
| B | GLY271 |
| B | ASP336 |
| B | GLY337 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1373 |
| Chain | Residue |
| B | TRP1 |
| B | HIS11 |
| B | ASP130 |
| B | ZN1375 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 1374 |
| Chain | Residue |
| B | HIS136 |
| B | HIS148 |
| B | GLU152 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 1375 |
| Chain | Residue |
| B | ASP56 |
| B | HIS68 |
| B | HIS126 |
| B | ASP130 |
| B | ZN1373 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA C 1371 |
| Chain | Residue |
| C | ASP293 |
| C | ASN294 |
| C | GLY296 |
| C | ASP298 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA C 1372 |
| Chain | Residue |
| C | ASP269 |
| C | GLY271 |
| C | ASP336 |
| C | GLY337 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1373 |
| Chain | Residue |
| C | TRP1 |
| C | HIS11 |
| C | ASP130 |
| C | ZN1375 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1374 |
| Chain | Residue |
| C | HIS136 |
| C | HIS148 |
| C | GLU152 |
| C | HOH2052 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 1375 |
| Chain | Residue |
| C | ASP56 |
| C | HIS68 |
| C | HIS126 |
| C | ASP130 |
| C | ZN1373 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 1371 |
| Chain | Residue |
| D | ASP269 |
| D | GLY271 |
| D | THR335 |
| D | ASP336 |
| D | GLY337 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 1372 |
| Chain | Residue |
| C | TYR219 |
| D | ASP293 |
| D | ASN294 |
| D | GLY296 |
| D | ASP298 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1373 |
| Chain | Residue |
| D | TRP1 |
| D | HIS11 |
| D | ASP130 |
| D | ZN1375 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1374 |
| Chain | Residue |
| D | HIS136 |
| D | HIS148 |
| D | GLU152 |
| D | HOH2081 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 1375 |
| Chain | Residue |
| D | ASP56 |
| D | HIS68 |
| D | HIS126 |
| D | ASP130 |
| D | ZN1373 |
Functional Information from PROSITE/UniProt
| site_id | PS00384 |
| Number of Residues | 14 |
| Details | PROKAR_ZN_DEPEND_PLPC_1 Prokaryotic zinc-dependent phospholipase C signature. HYfGDLNtPyHAaN |
| Chain | Residue | Details |
| A | HIS126-ASN139 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ah7 |
| Chain | Residue | Details |
| A | ASP56 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ah7 |
| Chain | Residue | Details |
| B | ASP56 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ah7 |
| Chain | Residue | Details |
| C | ASP56 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ah7 |
| Chain | Residue | Details |
| D | ASP56 |
