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1OJ1

Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with (2,5 CpG) and d(ApCpGpA)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0004519molecular_functionendonuclease activity
A0004540molecular_functionRNA nuclease activity
A0050830biological_processdefense response to Gram-positive bacterium
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A1107
ChainResidue
ALYS9
AHIS10
APHE98
ACG21106
AHOH2101
AHOH2107

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE CG2 A1106
ChainResidue
ALYS49
AASN50
AGLN67
AASN69
APHE98
AALA99
AGLY100
AVAL101
ASO41107
AHOH2106
AHIS10
AASN34
ATHR35

Functional Information from PROSITE/UniProt
site_idPS00127
Number of Residues7
DetailsRNASE_PANCREATIC Pancreatic ribonuclease family signature. CKktNTF
ChainResidueDetails
ACYS30-PHE36

226707

PDB entries from 2024-10-30

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