1OIX

X-ray structure of the small G protein Rab11a in complex with GDP and Pi

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE PO4 A 202

Chain	Residue
A	SER20
A	HOH2069
A	HOH2161
A	HOH2162
A	HOH2163
A	GLY21
A	LYS24
A	SER42
A	THR43
A	ALA68
A	GLY69
A	GDP201
A	MG301

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 301

Chain	Residue
A	SER25
A	THR43
A	GDP201
A	PO4202
A	HOH2069
A	HOH2161

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 401

Chain	Residue
A	ARG72
A	TYR73
A	HOH2019
A	HOH2072

---

site_id	AC4
Number of Residues	27
Details	BINDING SITE FOR RESIDUE GDP A 201

Chain	Residue
A	GLY21
A	VAL22
A	GLY23
A	LYS24
A	SER25
A	ASN26
A	PHE36
A	ASN37
A	LEU38
A	GLU39
A	SER40
A	ASN124
A	LYS125
A	ASP127
A	LEU128
A	SER154
A	ALA155
A	LEU156
A	PO4202
A	MG301
A	HOH2039
A	HOH2069
A	HOH2079
A	HOH2158
A	HOH2159
A	HOH2160
A	HOH2161

---

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL

Chain	Residue	Details
A	VAL14-LEU27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	SER20

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH, ECO:0007744|PDB:2HV8

Chain	Residue	Details
A	GLY21
A	ASP127
A	ALA155
A	LEU156
A	GLY23
A	LYS24
A	ASN26
A	ASN37
A	LEU38
A	SER40
A	GLY69
A	LYS125

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	VAL22

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15837192, ECO:0000269|PubMed:16034420, ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:1OIX, ECO:0007744|PDB:1YZK, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH, ECO:0007744|PDB:2HV8

Chain	Residue	Details
A	SER25
A	THR43

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	SER42

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD

Chain	Residue	Details
A	ASP66

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16905101, ECO:0000269|PubMed:17007872, ECO:0000269|PubMed:17030804, ECO:0007744|PDB:2D7C, ECO:0007744|PDB:2GZD, ECO:0007744|PDB:2GZH

Chain	Residue	Details
A	ASN124

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: N-acetylglycine => ECO:0000269|Ref.11

Chain	Residue	Details
A	GLY2

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32974215

Chain	Residue	Details
A	ARG4

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	LEU70

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	GLY21

---