1OHB

Acetylglutamate kinase from Escherichia coli complexed with ADP and sulphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003942	molecular_function	N-acetyl-gamma-glutamyl-phosphate reductase activity
A	0003991	molecular_function	acetylglutamate kinase activity
A	0004042	molecular_function	acetyl-CoA:L-glutamate N-acetyltransferase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006526	biological_process	arginine biosynthetic process
A	0006536	biological_process	glutamate metabolic process
A	0006974	biological_process	DNA damage response
A	0008652	biological_process	amino acid biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0042450	biological_process	arginine biosynthetic process via ornithine

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 A1259

Chain	Residue
A	LYS8
A	HOH2135
A	GLY10
A	GLY11
A	GLY43
A	GLY44
A	GLY45
A	ALA161
A	ADP1260
A	HOH2089

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A1261

Chain	Residue
A	LEU65
A	ARG66
A	VAL122
A	ASN158
A	HOH2088
A	HOH2137

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site_id	AC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP A1260

Chain	Residue
A	GLY10
A	GLY11
A	SER180
A	ASP181
A	ILE185
A	LEU186
A	ILE209
A	ILE210
A	THR211
A	MET214
A	LYS217
A	SO41259
A	HOH2099
A	HOH2136

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00082, ECO:0000269|PubMed:12005432, ECO:0000269|PubMed:12875848

Chain	Residue	Details
A	GLY44
A	ARG66
A	ASN158

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00082, ECO:0000269|PubMed:12875848

Chain	Residue	Details
A	ASP181
A	ILE209

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00082, ECO:0000305|PubMed:12875848

Chain	Residue	Details
A	LYS8
A	LYS217

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 870

Chain	Residue	Details
A	LYS8	transition state stabiliser
A	GLY11	transition state stabiliser
A	GLY45	transition state stabiliser
A	ASP162	activator, steric role
A	LYS217	transition state stabiliser

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