1OFQ

CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH MANGANESE(II)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009058	biological_process	biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0043085	biological_process	positive regulation of catalytic activity
A	0046417	biological_process	chorismate metabolic process
B	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009058	biological_process	biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0043085	biological_process	positive regulation of catalytic activity
B	0046417	biological_process	chorismate metabolic process
C	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0009058	biological_process	biosynthetic process
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0009423	biological_process	chorismate biosynthetic process
C	0043085	biological_process	positive regulation of catalytic activity
C	0046417	biological_process	chorismate metabolic process
D	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0009058	biological_process	biosynthetic process
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0009423	biological_process	chorismate biosynthetic process
D	0043085	biological_process	positive regulation of catalytic activity
D	0046417	biological_process	chorismate metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A1000

Chain	Residue
A	CYS1076
A	HIS1282
A	GLU1316
A	ASP1342

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN B2000

Chain	Residue
B	CYS2076
B	HIS2282
B	GLU2316
B	ASP2342

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN C3000

Chain	Residue
C	HIS3282
C	GLU3316
C	ASP3342
C	CYS3076

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D4000

Chain	Residue
D	HOH2002
D	CYS4076
D	HIS4282
D	GLU4316
D	ASP4342

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01406","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1q3n

Chain	Residue	Details
A	HIS1282

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1q3n

Chain	Residue	Details
B	HIS2282

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1q3n

Chain	Residue	Details
C	HIS3282

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1q3n

Chain	Residue	Details
D	HIS4282

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