1OFI
Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0009376 | cellular_component | HslUV protease complex |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0009376 | cellular_component | HslUV protease complex |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0009376 | cellular_component | HslUV protease complex |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| G | 0004298 | molecular_function | threonine-type endopeptidase activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005839 | cellular_component | proteasome core complex |
| G | 0006508 | biological_process | proteolysis |
| G | 0008233 | molecular_function | peptidase activity |
| G | 0009376 | cellular_component | HslUV protease complex |
| G | 0030163 | biological_process | protein catabolic process |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0051603 | biological_process | proteolysis involved in protein catabolic process |
| H | 0004298 | molecular_function | threonine-type endopeptidase activity |
| H | 0005515 | molecular_function | protein binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005839 | cellular_component | proteasome core complex |
| H | 0006508 | biological_process | proteolysis |
| H | 0008233 | molecular_function | peptidase activity |
| H | 0009376 | cellular_component | HslUV protease complex |
| H | 0030163 | biological_process | protein catabolic process |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0051603 | biological_process | proteolysis involved in protein catabolic process |
| I | 0004298 | molecular_function | threonine-type endopeptidase activity |
| I | 0005515 | molecular_function | protein binding |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005839 | cellular_component | proteasome core complex |
| I | 0006508 | biological_process | proteolysis |
| I | 0008233 | molecular_function | peptidase activity |
| I | 0009376 | cellular_component | HslUV protease complex |
| I | 0030163 | biological_process | protein catabolic process |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0051603 | biological_process | proteolysis involved in protein catabolic process |
| L | 0004298 | molecular_function | threonine-type endopeptidase activity |
| L | 0005515 | molecular_function | protein binding |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0005839 | cellular_component | proteasome core complex |
| L | 0006508 | biological_process | proteolysis |
| L | 0008233 | molecular_function | peptidase activity |
| L | 0009376 | cellular_component | HslUV protease complex |
| L | 0030163 | biological_process | protein catabolic process |
| L | 0046872 | molecular_function | metal ion binding |
| L | 0051603 | biological_process | proteolysis involved in protein catabolic process |
| M | 0004298 | molecular_function | threonine-type endopeptidase activity |
| M | 0005515 | molecular_function | protein binding |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0005839 | cellular_component | proteasome core complex |
| M | 0006508 | biological_process | proteolysis |
| M | 0008233 | molecular_function | peptidase activity |
| M | 0009376 | cellular_component | HslUV protease complex |
| M | 0030163 | biological_process | protein catabolic process |
| M | 0046872 | molecular_function | metal ion binding |
| M | 0051603 | biological_process | proteolysis involved in protein catabolic process |
| N | 0004298 | molecular_function | threonine-type endopeptidase activity |
| N | 0005515 | molecular_function | protein binding |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0005839 | cellular_component | proteasome core complex |
| N | 0006508 | biological_process | proteolysis |
| N | 0008233 | molecular_function | peptidase activity |
| N | 0009376 | cellular_component | HslUV protease complex |
| N | 0030163 | biological_process | protein catabolic process |
| N | 0046872 | molecular_function | metal ion binding |
| N | 0051603 | biological_process | proteolysis involved in protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PO4 A 452 |
| Chain | Residue |
| A | PRO58 |
| A | HOH2003 |
| A | HOH2005 |
| A | HOH2007 |
| A | THR59 |
| A | LYS63 |
| A | GLU258 |
| A | GLU322 |
| A | ADP450 |
| A | MG451 |
| A | MG453 |
| A | HOH2002 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 B 452 |
| Chain | Residue |
| B | PRO58 |
| B | THR59 |
| B | GLY60 |
| B | LYS63 |
| B | GLU258 |
| B | ADP450 |
| B | MG451 |
| B | MG453 |
| B | HOH2004 |
| C | GLU322 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 C 452 |
| Chain | Residue |
| B | GLU322 |
| C | PRO58 |
| C | THR59 |
| C | GLY60 |
| C | GLU258 |
| C | ADP450 |
| C | MG451 |
| C | MG453 |
| C | HOH2002 |
| C | HOH2006 |
| C | HOH2007 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG G 454 |
| Chain | Residue |
| G | GLY157 |
| G | CYS160 |
| G | THR163 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG H 454 |
| Chain | Residue |
| H | GLY157 |
| H | CYS160 |
| H | THR163 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG I 454 |
| Chain | Residue |
| I | GLY157 |
| I | CYS160 |
| I | THR163 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG L 454 |
| Chain | Residue |
| L | GLY157 |
| L | CYS160 |
| L | VAL161 |
| L | THR163 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG M 454 |
| Chain | Residue |
| M | GLY157 |
| M | CYS160 |
| M | THR163 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG N 454 |
| Chain | Residue |
| N | GLY157 |
| N | CYS160 |
| N | THR163 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 451 |
| Chain | Residue |
| A | ADP450 |
| A | PO4452 |
| A | HOH2001 |
| A | HOH2002 |
| A | HOH2006 |
| A | HOH2007 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 453 |
| Chain | Residue |
| A | GLU258 |
| A | GLU322 |
| A | PO4452 |
| A | HOH2003 |
| A | HOH2004 |
| A | HOH2005 |
| A | HOH2007 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 451 |
| Chain | Residue |
| B | ADP450 |
| B | PO4452 |
| B | HOH2001 |
| B | HOH2004 |
| B | HOH2005 |
| B | HOH2006 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 453 |
| Chain | Residue |
| B | GLU258 |
| B | PO4452 |
| B | HOH2002 |
| B | HOH2007 |
| C | GLU322 |
| C | HOH2004 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 451 |
| Chain | Residue |
| C | ADP450 |
| C | PO4452 |
| C | HOH2001 |
| C | HOH2002 |
| C | HOH2005 |
| C | HOH2007 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 453 |
| Chain | Residue |
| B | GLU322 |
| B | HOH2003 |
| C | GLU258 |
| C | PO4452 |
| C | HOH2003 |
| C | HOH2006 |
| site_id | BC7 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP A 450 |
| Chain | Residue |
| A | GLU65 |
| A | GLU287 |
| A | LEU336 |
| A | ALA393 |
| A | MG451 |
| A | PO4452 |
| A | HOH2001 |
| A | HOH2006 |
| A | HIS16 |
| A | ILE17 |
| A | ILE18 |
| A | PRO58 |
| A | THR59 |
| A | GLY60 |
| A | VAL61 |
| A | GLY62 |
| A | LYS63 |
| A | THR64 |
| site_id | BC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP B 450 |
| Chain | Residue |
| B | HIS16 |
| B | ILE17 |
| B | ILE18 |
| B | GLN20 |
| B | PRO58 |
| B | GLY60 |
| B | VAL61 |
| B | GLY62 |
| B | LYS63 |
| B | THR64 |
| B | GLU65 |
| B | LEU336 |
| B | ALA393 |
| B | MG451 |
| B | PO4452 |
| B | HOH2004 |
| B | HOH2005 |
| B | HOH2006 |
| site_id | BC9 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP C 450 |
| Chain | Residue |
| C | HIS16 |
| C | ILE17 |
| C | ILE18 |
| C | PRO58 |
| C | THR59 |
| C | GLY60 |
| C | VAL61 |
| C | GLY62 |
| C | LYS63 |
| C | THR64 |
| C | GLU65 |
| C | ALA393 |
| C | MG451 |
| C | PO4452 |
| C | HOH2005 |
| site_id | CC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE LVS G 0 |
| Chain | Residue |
| G | THR1 |
| G | GLN19 |
| G | VAL20 |
| G | SER21 |
| G | MET27 |
| G | LYS33 |
| G | PHE46 |
| G | ALA47 |
| G | GLY48 |
| G | THR50 |
| G | THR107 |
| G | ILE109 |
| G | ASP111 |
| G | GLY124 |
| G | SER125 |
| site_id | CC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE LVS H 0 |
| Chain | Residue |
| H | THR1 |
| H | VAL20 |
| H | SER21 |
| H | LYS33 |
| H | PHE46 |
| H | ALA47 |
| H | GLY48 |
| H | THR50 |
| H | GLY124 |
| H | SER125 |
| I | THR107 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE LVS I 0 |
| Chain | Residue |
| H | GLU92 |
| I | THR1 |
| I | VAL20 |
| I | SER21 |
| I | PHE46 |
| I | GLY48 |
| I | THR50 |
| I | GLY124 |
| I | SER125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| G | THR2 | |
| H | THR2 | |
| I | THR2 | |
| L | THR2 | |
| M | THR2 | |
| N | THR2 | |
| C | ILE18 | |
| C | GLY60 | |
| C | ILE306 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | BINDING: |
| Chain | Residue | Details |
| G | ASP158 | |
| L | ASP158 | |
| L | VAL161 | |
| L | ASN164 | |
| M | ASP158 | |
| M | VAL161 | |
| M | ASN164 | |
| N | ASP158 | |
| N | VAL161 | |
| N | ASN164 | |
| G | VAL161 | |
| G | ASN164 | |
| H | ASP158 | |
| H | VAL161 | |
| H | ASN164 | |
| I | ASP158 | |
| I | VAL161 | |
| I | ASN164 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| G | GLY48 | |
| G | LYS33 | |
| G | THR1 | |
| G | SER125 |
| site_id | CSA10 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| L | GLY45 | |
| L | LYS33 | |
| L | THR1 | |
| L | SER125 |
| site_id | CSA11 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| M | GLY45 | |
| M | LYS33 | |
| M | THR1 | |
| M | SER125 |
| site_id | CSA12 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| N | GLY45 | |
| N | LYS33 | |
| N | THR1 | |
| N | SER125 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| H | GLY48 | |
| H | LYS33 | |
| H | THR1 | |
| H | SER125 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| I | GLY48 | |
| I | LYS33 | |
| I | THR1 | |
| I | SER125 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| L | GLY48 | |
| L | LYS33 | |
| L | THR1 | |
| L | SER125 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| M | GLY48 | |
| M | LYS33 | |
| M | THR1 | |
| M | SER125 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| N | GLY48 | |
| N | LYS33 | |
| N | THR1 | |
| N | SER125 |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| G | GLY45 | |
| G | LYS33 | |
| G | THR1 | |
| G | SER125 |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| H | GLY45 | |
| H | LYS33 | |
| H | THR1 | |
| H | SER125 |
| site_id | CSA9 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pma |
| Chain | Residue | Details |
| I | GLY45 | |
| I | LYS33 | |
| I | THR1 | |
| I | SER125 |
