Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SER A 401 |
| Chain | Residue |
| A | GLY37 |
| A | TYR78 |
| A | GLY79 |
| A | ILE216 |
| A | ASP218 |
| A | THR402 |
| A | HOH2586 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE THR A 402 |
| Chain | Residue |
| A | SER401 |
| A | HOH2587 |
| A | HOH2588 |
| A | HOH2589 |
| A | GLY37 |
| A | SER77 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 410 |
| Chain | Residue |
| A | CYS254 |
| A | ASP278 |
| A | GLY280 |
| A | PRO281 |
| A | CYS289 |
| A | HOH2590 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 500 |
| Chain | Residue |
| A | TYR178 |
| A | SER181 |
| A | ILE182 |
| A | HOH2413 |
| A | HOH2591 |
| A | HOH2592 |
| A | HOH2593 |
| A | HOH2594 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | SER112 |
| A | SER113 |
| A | THR320 |
| A | THR321 |
| A | HOH2310 |
| A | HOH2595 |
| A | HOH2596 |
| A | HOH2597 |
| A | HOH2598 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | SER136 |
| A | PRO137 |
| A | HOH2599 |
| A | HOH2600 |
| A | HOH2601 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | ALA268 |
| A | ARG269 |
| A | SER283 |
| A | HOH2415 |
| A | HOH2544 |
| A | HOH2581 |
| A | HOH2602 |
| A | HOH2603 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 504 |
| Chain | Residue |
| A | LYS141 |
| A | HOH2604 |
| A | HOH2605 |
| A | HOH2606 |
| A | HOH2608 |
| A | HOH2609 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | ILE216-PRO227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP35 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP218 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | SER38 | |
| A | ASP35 | |
| A | ASP218 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP35 | |
| A | ASP218 | |
| A | THR219 | |
| A | THR36 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER38 | |
| A | ASP35 | |
| A | ASP218 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | ASP35 | |
| A | ASP218 | |
| A | THR36 | |
