1ODT
cephalosporin C deacetylase mutated, in complex with acetate
Functional Information from GO Data
Chain | GOid | namespace | contents |
C | 0005737 | cellular_component | cytoplasm |
C | 0005976 | biological_process | polysaccharide metabolic process |
C | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
C | 0030245 | biological_process | cellulose catabolic process |
C | 0046555 | molecular_function | acetylxylan esterase activity |
C | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
C | 0052689 | molecular_function | carboxylic ester hydrolase activity |
H | 0005737 | cellular_component | cytoplasm |
H | 0005976 | biological_process | polysaccharide metabolic process |
H | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
H | 0030245 | biological_process | cellulose catabolic process |
H | 0046555 | molecular_function | acetylxylan esterase activity |
H | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
H | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE ACT C1318 |
Chain | Residue |
C | GLY90 |
C | TYR91 |
C | ALA181 |
C | GLN182 |
C | TYR206 |
C | PRO221 |
C | HIS298 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE ACT H1318 |
Chain | Residue |
H | ALA181 |
H | GLN182 |
H | HIS298 |
H | HOH2274 |
H | GLY90 |
H | TYR91 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Nucleophile |
Chain | Residue | Details |
C | ALA181 | |
H | ALA181 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
C | ASP269 | |
C | HIS298 | |
H | ASP269 | |
H | HIS298 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: |
Chain | Residue | Details |
C | TYR91 | |
H | TYR91 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 866 |
Chain | Residue | Details |
C | TYR91 | electrostatic stabiliser |
C | ALA181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
C | GLN182 | electrostatic stabiliser |
C | ASP269 | electrostatic stabiliser, increase basicity |
C | HIS298 | proton acceptor, proton donor |
site_id | MCSA2 |
Number of Residues | 5 |
Details | M-CSA 866 |
Chain | Residue | Details |
H | TYR91 | electrostatic stabiliser |
H | ALA181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
H | GLN182 | electrostatic stabiliser |
H | ASP269 | electrostatic stabiliser, increase basicity |
H | HIS298 | proton acceptor, proton donor |