1ODS
Cephalosporin C deacetylase from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005976 | biological_process | polysaccharide metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0030245 | biological_process | cellulose catabolic process |
| A | 0046555 | molecular_function | acetylxylan esterase activity |
| A | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005976 | biological_process | polysaccharide metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0030245 | biological_process | cellulose catabolic process |
| B | 0046555 | molecular_function | acetylxylan esterase activity |
| B | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| B | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| C | 0000272 | biological_process | polysaccharide catabolic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005976 | biological_process | polysaccharide metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| C | 0030245 | biological_process | cellulose catabolic process |
| C | 0046555 | molecular_function | acetylxylan esterase activity |
| C | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| C | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| D | 0000272 | biological_process | polysaccharide catabolic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005976 | biological_process | polysaccharide metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| D | 0030245 | biological_process | cellulose catabolic process |
| D | 0046555 | molecular_function | acetylxylan esterase activity |
| D | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| D | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| E | 0000272 | biological_process | polysaccharide catabolic process |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005976 | biological_process | polysaccharide metabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| E | 0030245 | biological_process | cellulose catabolic process |
| E | 0046555 | molecular_function | acetylxylan esterase activity |
| E | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| E | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| F | 0000272 | biological_process | polysaccharide catabolic process |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005976 | biological_process | polysaccharide metabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| F | 0030245 | biological_process | cellulose catabolic process |
| F | 0046555 | molecular_function | acetylxylan esterase activity |
| F | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| F | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| G | 0000272 | biological_process | polysaccharide catabolic process |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005976 | biological_process | polysaccharide metabolic process |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| G | 0030245 | biological_process | cellulose catabolic process |
| G | 0046555 | molecular_function | acetylxylan esterase activity |
| G | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| G | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| H | 0000272 | biological_process | polysaccharide catabolic process |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005976 | biological_process | polysaccharide metabolic process |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| H | 0030245 | biological_process | cellulose catabolic process |
| H | 0046555 | molecular_function | acetylxylan esterase activity |
| H | 0047739 | molecular_function | cephalosporin-C deacetylase activity |
| H | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A1318 |
| Chain | Residue |
| A | SER129 |
| A | PRO130 |
| A | HIS131 |
| A | GLY132 |
| A | HIS133 |
| A | GLY141 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A1319 |
| Chain | Residue |
| A | HOH2193 |
| A | HOH2099 |
| A | HOH2189 |
| A | HOH2192 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1320 |
| Chain | Residue |
| A | HOH2078 |
| A | HOH2082 |
| D | HOH2030 |
| D | HOH2032 |
| D | HOH2079 |
| D | HOH2082 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B1318 |
| Chain | Residue |
| B | SER129 |
| B | PRO130 |
| B | HIS131 |
| B | GLY132 |
| B | HIS133 |
| B | GLY141 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C1318 |
| Chain | Residue |
| C | SER129 |
| C | PRO130 |
| C | HIS131 |
| C | GLY132 |
| C | HIS133 |
| C | GLY141 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL D1318 |
| Chain | Residue |
| D | SER129 |
| D | PRO130 |
| D | HIS131 |
| D | GLY132 |
| D | HIS133 |
| D | GLY141 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL E1318 |
| Chain | Residue |
| E | SER129 |
| E | PRO130 |
| E | HIS131 |
| E | GLY132 |
| E | HIS133 |
| E | GLY141 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL F1318 |
| Chain | Residue |
| F | SER129 |
| F | PRO130 |
| F | HIS131 |
| F | GLY132 |
| F | HIS133 |
| F | GLY141 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL G1318 |
| Chain | Residue |
| G | SER129 |
| G | PRO130 |
| G | HIS131 |
| G | GLY132 |
| G | HIS133 |
| G | GLY141 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL H1318 |
| Chain | Residue |
| H | SER129 |
| H | PRO130 |
| H | HIS131 |
| H | GLY132 |
| H | HIS133 |
| H | GLY141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Nucleophile"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Active site: {"description":"Charge relay system"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| A | SER181 | |
| A | ASP269 | |
| A | HIS298 | |
| A | GLN182 |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| B | SER181 | |
| B | HIS298 | |
| B | ASP269 |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| C | SER181 | |
| C | HIS298 | |
| C | ASP269 |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| D | SER181 | |
| D | HIS298 | |
| D | ASP269 |
| site_id | CSA13 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| E | SER181 | |
| E | HIS298 | |
| E | ASP269 |
| site_id | CSA14 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| F | SER181 | |
| F | HIS298 | |
| F | ASP269 |
| site_id | CSA15 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| G | SER181 | |
| G | HIS298 | |
| G | ASP269 |
| site_id | CSA16 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| H | SER181 | |
| H | HIS298 | |
| H | ASP269 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| B | SER181 | |
| B | ASP269 | |
| B | HIS298 | |
| B | GLN182 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| C | SER181 | |
| C | ASP269 | |
| C | HIS298 | |
| C | GLN182 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| D | SER181 | |
| D | ASP269 | |
| D | HIS298 | |
| D | GLN182 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| E | SER181 | |
| E | ASP269 | |
| E | HIS298 | |
| E | GLN182 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| F | SER181 | |
| F | ASP269 | |
| F | HIS298 | |
| F | GLN182 |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| G | SER181 | |
| G | ASP269 | |
| G | HIS298 | |
| G | GLN182 |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| H | SER181 | |
| H | ASP269 | |
| H | HIS298 | |
| H | GLN182 |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1odt |
| Chain | Residue | Details |
| A | SER181 | |
| A | HIS298 | |
| A | ASP269 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| A | TYR91 | electrostatic stabiliser |
| A | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | GLN182 | electrostatic stabiliser |
| A | ASP269 | electrostatic stabiliser, increase basicity |
| A | HIS298 | proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| B | TYR91 | electrostatic stabiliser |
| B | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | GLN182 | electrostatic stabiliser |
| B | ASP269 | electrostatic stabiliser, increase basicity |
| B | HIS298 | proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| C | TYR91 | electrostatic stabiliser |
| C | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| C | GLN182 | electrostatic stabiliser |
| C | ASP269 | electrostatic stabiliser, increase basicity |
| C | HIS298 | proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| D | TYR91 | electrostatic stabiliser |
| D | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| D | GLN182 | electrostatic stabiliser |
| D | ASP269 | electrostatic stabiliser, increase basicity |
| D | HIS298 | proton acceptor, proton donor |
| site_id | MCSA5 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| E | TYR91 | electrostatic stabiliser |
| E | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| E | GLN182 | electrostatic stabiliser |
| E | ASP269 | electrostatic stabiliser, increase basicity |
| E | HIS298 | proton acceptor, proton donor |
| site_id | MCSA6 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| F | TYR91 | electrostatic stabiliser |
| F | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| F | GLN182 | electrostatic stabiliser |
| F | ASP269 | electrostatic stabiliser, increase basicity |
| F | HIS298 | proton acceptor, proton donor |
| site_id | MCSA7 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| G | TYR91 | electrostatic stabiliser |
| G | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| G | GLN182 | electrostatic stabiliser |
| G | ASP269 | electrostatic stabiliser, increase basicity |
| G | HIS298 | proton acceptor, proton donor |
| site_id | MCSA8 |
| Number of Residues | 5 |
| Details | M-CSA 866 |
| Chain | Residue | Details |
| H | TYR91 | electrostatic stabiliser |
| H | SER181 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, proton acceptor, proton donor |
| H | GLN182 | electrostatic stabiliser |
| H | ASP269 | electrostatic stabiliser, increase basicity |
| H | HIS298 | proton acceptor, proton donor |
