1OCB
Structure of the wild-type cellobiohydrolase Cel6A from Humicolas insolens in complex with a fluorescent substrate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0030245 | biological_process | cellulose catabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0030245 | biological_process | cellulose catabolic process |
Functional Information from PROSITE/UniProt
| site_id | PS00655 |
| Number of Residues | 17 |
| Details | GLYCOSYL_HYDROL_F6_1 Glycosyl hydrolases family 6 signature 1. VvYdlPdRDCAaaASnG |
| Chain | Residue | Details |
| A | VAL172-GLY188 |
| site_id | PS00656 |
| Number of Residues | 10 |
| Details | GLYCOSYL_HYDROL_F6_2 Glycosyl hydrolases family 6 signature 2. ILVIEPDSLA |
| Chain | Residue | Details |
| A | ILE220-ALA229 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 44 |
| Details | Region: {"description":"Substrate binding loop 1","evidences":[{"source":"PubMed","id":"10413461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12454501","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12842048","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Region: {"description":"Substrate binding loop 2","evidences":[{"source":"PubMed","id":"10413461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12454501","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12842048","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10057","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10413461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12842048","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10056","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10413461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12454501","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12842048","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10413461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12454501","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12842048","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"O-linked (Man...) threonine","evidences":[{"source":"PubMed","id":"9882628","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"O-linked (Man...) serine","evidences":[{"source":"PubMed","id":"9882628","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10413461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12454501","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12842048","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9882628","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1qk2 |
| Chain | Residue | Details |
| A | ARG179 | |
| A | ASP226 | |
| A | ASP180 | |
| A | TYR174 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1qk2 |
| Chain | Residue | Details |
| B | ARG179 | |
| B | ASP226 | |
| B | ASP180 | |
| B | TYR174 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qk2 |
| Chain | Residue | Details |
| A | ASP226 | |
| A | ASP405 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qk2 |
| Chain | Residue | Details |
| B | ASP226 | |
| B | ASP405 |
