1OC3
HUMAN PEROXIREDOXIN 5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008379 | molecular_function | thioredoxin peroxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0008379 | molecular_function | thioredoxin peroxidase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| C | 0008379 | molecular_function | thioredoxin peroxidase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0034599 | biological_process | cellular response to oxidative stress |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BEZ A 201 |
| Chain | Residue |
| A | PRO40 |
| A | THR44 |
| A | GLY46 |
| A | CYS47 |
| A | ARG127 |
| C | ALA64 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BEZ B 201 |
| Chain | Residue |
| B | PRO40 |
| B | THR44 |
| B | GLY46 |
| B | CYS47 |
| B | ARG127 |
| A | LYS63 |
| A | ALA64 |
| A | GLY66 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000305|PubMed:10751410, ECO:0000305|PubMed:20643143 |
| Chain | Residue | Details |
| A | CYS47 | |
| B | CYS47 | |
| C | CYS47 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P99029 |
| Chain | Residue | Details |
| A | LYS22 | |
| B | LYS22 | |
| C | LYS22 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P99029 |
| Chain | Residue | Details |
| A | LYS30 | |
| B | LYS30 | |
| C | LYS30 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P99029 |
| Chain | Residue | Details |
| A | LYS63 | |
| B | LYS63 | |
| C | LYS63 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9R063 |
| Chain | Residue | Details |
| A | SER118 | |
| B | SER118 | |
| C | SER118 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P99029 |
| Chain | Residue | Details |
| A | SER129 | |
| B | SER129 | |
| C | SER129 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:31740833 |
| Chain | Residue | Details |
| A | CYS47 | |
| B | CYS47 | |
| C | CYS47 |
