Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 308 |
| Chain | Residue |
| A | ARG122 |
| A | GLY127 |
| A | SER128 |
| A | ARG242 |
| A | HOH2323 |
| A | HOH2519 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 309 |
| Chain | Residue |
| A | HIS110 |
| A | HOH2183 |
| A | HOH2520 |
| A | HOH2521 |
| A | HOH2522 |
| A | HOH2523 |
| A | ARG73 |
| A | ASN74 |
| A | ASP78 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 310 |
| Chain | Residue |
| A | ATP307 |
| A | HOH2397 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 311 |
| Chain | Residue |
| A | SER61 |
| A | GLU234 |
| A | VAL235 |
| A | HOH2150 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE ATP A 307 |
| Chain | Residue |
| A | GLY18 |
| A | LYS19 |
| A | ARG21 |
| A | ILE23 |
| A | LEU31 |
| A | PHE33 |
| A | HIS75 |
| A | HIS110 |
| A | HIS112 |
| A | LYS143 |
| A | GLU219 |
| A | VAL232 |
| A | ASP233 |
| A | MG310 |
| A | HOH2397 |
| A | HOH2508 |
| A | HOH2509 |
| A | HOH2510 |
| A | HOH2511 |
| A | HOH2512 |
| A | HOH2513 |
| A | HOH2514 |
| A | HOH2515 |
| A | HOH2516 |
| A | HOH2517 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AMP A 315 |
| Chain | Residue |
| A | GLU62 |
| A | VAL77 |
| A | ILE79 |
| A | ILE85 |
| A | SER106 |
| A | LEU107 |
| A | LEU108 |
| A | HOH2524 |
| A | HOH2525 |
| A | HOH2526 |
Functional Information from PROSITE/UniProt
| site_id | PS01057 |
| Number of Residues | 15 |
| Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. LIPLEvIVRgyiTGS |
| Chain | Residue | Details |
| A | LEU114-SER128 | |
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. IADtKFEFG |
| Chain | Residue | Details |
| A | ILE213-GLY221 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"9551557","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
