1OB5

T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003746	molecular_function	translation elongation factor activity
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006414	biological_process	translational elongation
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003746	molecular_function	translation elongation factor activity
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006414	biological_process	translational elongation
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0003746	molecular_function	translation elongation factor activity
E	0003924	molecular_function	GTPase activity
E	0005525	molecular_function	GTP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006412	biological_process	translation
E	0006414	biological_process	translational elongation
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GNP A 1406

Chain	Residue
A	VAL20
A	GLY84
A	HIS85
A	ASN136
A	LYS137
A	ASP139
A	MET140
A	SER174
A	ALA175
A	LEU176
A	MG1407
A	ASP21
A	GLY23
A	LYS24
A	THR25
A	THR26
A	TYR47
A	ILE61
A	THR62

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1407

Chain	Residue
A	LYS24
A	THR25
A	THR62
A	ASP81
A	CYS82
A	GNP1406

---

site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ENX A 1408

Chain	Residue
A	ARG117
A	LEU121
A	ARG124
A	GLN125
A	VAL126
A	GLY127
A	TYR161
A	LEU323
A	LYS325
A	GLU326
A	GLU327
A	GLY328
A	TYR343
A	ARG345
A	PHE386
A	ALA387
A	ALA397

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GNP C 1406

Chain	Residue
C	VAL20
C	ASP21
C	GLY23
C	LYS24
C	THR25
C	THR26
C	TYR47
C	ILE61
C	THR62
C	GLY84
C	HIS85
C	ASN136
C	LYS137
C	ASP139
C	MET140
C	SER174
C	ALA175
C	LEU176
C	MG1407

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 1407

Chain	Residue
C	LYS24
C	THR25
C	THR62
C	ASP81
C	CYS82
C	GNP1406

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ENX C 1408

Chain	Residue
C	ARG117
C	LEU121
C	ARG124
C	GLN125
C	VAL126
C	GLY127
C	TYR161
C	LEU323
C	LYS325
C	GLU326
C	GLU327
C	GLY328
C	TYR343
C	ARG345
C	PHE386
C	ALA387
C	ALA397

---

site_id	AC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GNP E 1406

Chain	Residue
E	SER174
E	ALA175
E	LEU176
E	MG1407
E	VAL20
E	ASP21
E	GLY23
E	LYS24
E	THR25
E	THR26
E	TYR47
E	ILE61
E	THR62
E	GLY84
E	HIS85
E	ASN136
E	LYS137
E	ASP139
E	MET140

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 1407

Chain	Residue
E	LYS24
E	THR25
E	THR62
E	ASP81
E	CYS82
E	GNP1406

---

site_id	AC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ENX E 1408

Chain	Residue
E	ARG117
E	LEU121
E	ARG124
E	GLN125
E	VAL126
E	GLY127
E	TYR161
E	LEU323
E	LYS325
E	GLU326
E	GLU327
E	GLY328
E	TYR343
E	ARG345
E	PHE386
E	ALA387
E	ALA397

---

Functional Information from PROSITE/UniProt

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DKapeERaRGITIntA

Chain	Residue	Details
A	ASP51-ALA66

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	615
Details	Domain: {"description":"tr-type G"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	21
Details	Region: {"description":"G1","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Region: {"description":"G2","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	Region: {"description":"G3","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Region: {"description":"G4","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Region: {"description":"G5","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	42
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00118","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	ASP21

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	ASP21

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
E	ASP21

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	HIS85

---

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	HIS85

---

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
E	HIS85

---