1O9I
Crystal structure of the Y42F mutant of manganese catalase from Lactobacillus plantarum at 1.33A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0004096 | molecular_function | catalase activity |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0004096 | molecular_function | catalase activity |
| D | 0098869 | biological_process | cellular oxidant detoxification |
| E | 0004096 | molecular_function | catalase activity |
| E | 0098869 | biological_process | cellular oxidant detoxification |
| F | 0004096 | molecular_function | catalase activity |
| F | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 269 |
| Chain | Residue |
| A | ASP57 |
| A | ASP61 |
| F | ASN218 |
| F | SER220 |
| F | GLY222 |
| F | HOH2198 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 400 |
| Chain | Residue |
| F | LYS255 |
| F | GLY257 |
| F | HOH2230 |
| F | HOH2231 |
| A | HOH2066 |
| A | HOH2102 |
| A | HOH2103 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 401 |
| Chain | Residue |
| D | LYS255 |
| D | GLY257 |
| D | HOH2098 |
| D | HOH2227 |
| E | HOH2073 |
| E | HOH2077 |
| E | HOH2117 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 269 |
| Chain | Residue |
| B | ASP57 |
| B | ASP61 |
| C | ASN218 |
| C | SER220 |
| C | GLY222 |
| C | HOH2197 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 269 |
| Chain | Residue |
| B | ASN218 |
| B | SER220 |
| B | GLY222 |
| B | HOH2194 |
| C | ASP57 |
| C | ASP61 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 269 |
| Chain | Residue |
| D | ASP57 |
| D | ASP61 |
| D | HOH2065 |
| E | ASN218 |
| E | SER220 |
| E | GLY222 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA E 269 |
| Chain | Residue |
| D | ASN218 |
| D | SER220 |
| D | GLY222 |
| D | HOH2192 |
| E | ASP57 |
| E | ASP61 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA F 269 |
| Chain | Residue |
| A | ASN218 |
| A | SER220 |
| A | GLY222 |
| F | ASP57 |
| F | ASP61 |
| F | HOH2067 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 A 267 |
| Chain | Residue |
| A | GLU35 |
| A | GLU66 |
| A | HIS69 |
| A | MN3268 |
| A | O270 |
| A | HOH2228 |
| A | HOH2229 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 A 268 |
| Chain | Residue |
| A | GLU66 |
| A | ARG147 |
| A | GLU148 |
| A | HIS181 |
| A | MN3267 |
| A | O270 |
| A | HOH2228 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE O A 270 |
| Chain | Residue |
| A | GLU66 |
| A | HIS69 |
| A | GLU148 |
| A | HIS181 |
| A | MN3267 |
| A | MN3268 |
| A | HOH2228 |
| A | HOH2229 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES A 273 |
| Chain | Residue |
| A | PRO259 |
| A | HOH2230 |
| A | HOH2231 |
| A | HOH2232 |
| D | HOH2177 |
| F | GLU89 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 B 267 |
| Chain | Residue |
| B | GLU35 |
| B | GLU66 |
| B | HIS69 |
| B | MN3268 |
| B | O270 |
| B | HOH2241 |
| B | HOH2242 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 B 268 |
| Chain | Residue |
| B | GLU66 |
| B | ARG147 |
| B | GLU148 |
| B | HIS181 |
| B | MN3267 |
| B | O270 |
| B | HOH2241 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE O B 270 |
| Chain | Residue |
| B | GLU66 |
| B | HIS69 |
| B | HIS181 |
| B | MN3267 |
| B | MN3268 |
| B | HOH2241 |
| B | HOH2242 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 C 267 |
| Chain | Residue |
| C | GLU35 |
| C | GLU66 |
| C | HIS69 |
| C | MN3268 |
| C | O270 |
| C | HOH2241 |
| C | HOH2242 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 C 268 |
| Chain | Residue |
| C | GLU66 |
| C | ARG147 |
| C | GLU148 |
| C | HIS181 |
| C | MN3267 |
| C | O270 |
| C | HOH2241 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE O C 270 |
| Chain | Residue |
| C | GLU66 |
| C | HIS69 |
| C | GLU148 |
| C | HIS181 |
| C | MN3267 |
| C | MN3268 |
| C | HOH2241 |
| C | HOH2242 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 D 267 |
| Chain | Residue |
| D | GLU35 |
| D | GLU66 |
| D | HIS69 |
| D | MN3268 |
| D | O270 |
| D | HOH2242 |
| D | HOH2243 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 D 268 |
| Chain | Residue |
| D | GLU66 |
| D | ARG147 |
| D | GLU148 |
| D | HIS181 |
| D | MN3267 |
| D | O270 |
| D | HOH2243 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE O D 270 |
| Chain | Residue |
| D | GLU66 |
| D | HIS69 |
| D | GLU148 |
| D | HIS181 |
| D | MN3267 |
| D | MN3268 |
| D | HOH2242 |
| D | HOH2243 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 E 267 |
| Chain | Residue |
| E | GLU35 |
| E | GLU66 |
| E | HIS69 |
| E | MN3268 |
| E | O270 |
| E | HOH2245 |
| E | HOH2246 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 E 268 |
| Chain | Residue |
| E | GLU66 |
| E | ARG147 |
| E | GLU148 |
| E | HIS181 |
| E | MN3267 |
| E | O270 |
| E | HOH2245 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE O E 270 |
| Chain | Residue |
| E | GLU66 |
| E | HIS69 |
| E | GLU148 |
| E | HIS181 |
| E | MN3267 |
| E | MN3268 |
| E | HOH2245 |
| E | HOH2246 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES E 273 |
| Chain | Residue |
| A | HOH2134 |
| E | LYS92 |
| E | PRO259 |
| E | HOH2247 |
| E | HOH2248 |
| F | HOH2181 |
| site_id | CC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MES E 274 |
| Chain | Residue |
| D | PRO14 |
| D | ARG16 |
| D | SER17 |
| D | TYR79 |
| D | GLU82 |
| E | ARG16 |
| E | SER17 |
| E | LYS255 |
| site_id | CC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 F 267 |
| Chain | Residue |
| F | GLU35 |
| F | GLU66 |
| F | HIS69 |
| F | MN3268 |
| F | O270 |
| F | HOH2248 |
| F | HOH2249 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN3 F 268 |
| Chain | Residue |
| F | GLU66 |
| F | ARG147 |
| F | GLU148 |
| F | HIS181 |
| F | MN3267 |
| F | O270 |
| F | HOH2249 |
| site_id | DC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE O F 270 |
| Chain | Residue |
| F | GLU66 |
| F | HIS69 |
| F | GLU148 |
| F | HIS181 |
| F | MN3267 |
| F | MN3268 |
| F | HOH2248 |
| F | HOH2249 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MES F 273 |
| Chain | Residue |
| A | GLY250 |
| A | ILE251 |
| F | LYS7 |
| F | HOH2250 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES F 274 |
| Chain | Residue |
| B | GLU89 |
| C | ARG260 |
| F | SER160 |
| F | ARG168 |
| F | HOH2143 |
| F | HOH2251 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 138 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 60 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11587647","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12631270","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JKV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O9I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12631270, 10413487, 11587647 |
| Chain | Residue | Details |
| A | GLU178 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12631270, 10413487, 11587647 |
| Chain | Residue | Details |
| B | GLU178 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12631270, 10413487, 11587647 |
| Chain | Residue | Details |
| C | GLU178 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12631270, 10413487, 11587647 |
| Chain | Residue | Details |
| D | GLU178 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12631270, 10413487, 11587647 |
| Chain | Residue | Details |
| E | GLU178 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12631270, 10413487, 11587647 |
| Chain | Residue | Details |
| F | GLU178 |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 572 |
| Chain | Residue | Details |
| A | GLU35 | metal ligand |
| A | GLU66 | metal ligand |
| A | HIS69 | metal ligand |
| A | GLU148 | metal ligand |
| A | GLU178 | proton acceptor, proton donor, proton shuttle (general acid/base) |
| A | HIS181 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 572 |
| Chain | Residue | Details |
| B | GLU35 | metal ligand |
| B | GLU66 | metal ligand |
| B | HIS69 | metal ligand |
| B | GLU148 | metal ligand |
| B | GLU178 | proton acceptor, proton donor, proton shuttle (general acid/base) |
| B | HIS181 | metal ligand |
| site_id | MCSA3 |
| Number of Residues | 6 |
| Details | M-CSA 572 |
| Chain | Residue | Details |
| C | GLU35 | metal ligand |
| C | GLU66 | metal ligand |
| C | HIS69 | metal ligand |
| C | GLU148 | metal ligand |
| C | GLU178 | proton acceptor, proton donor, proton shuttle (general acid/base) |
| C | HIS181 | metal ligand |
| site_id | MCSA4 |
| Number of Residues | 6 |
| Details | M-CSA 572 |
| Chain | Residue | Details |
| D | GLU35 | metal ligand |
| D | GLU66 | metal ligand |
| D | HIS69 | metal ligand |
| D | GLU148 | metal ligand |
| D | GLU178 | proton acceptor, proton donor, proton shuttle (general acid/base) |
| D | HIS181 | metal ligand |
| site_id | MCSA5 |
| Number of Residues | 6 |
| Details | M-CSA 572 |
| Chain | Residue | Details |
| E | GLU35 | metal ligand |
| E | GLU66 | metal ligand |
| E | HIS69 | metal ligand |
| E | GLU148 | metal ligand |
| E | GLU178 | proton acceptor, proton donor, proton shuttle (general acid/base) |
| E | HIS181 | metal ligand |
| site_id | MCSA6 |
| Number of Residues | 6 |
| Details | M-CSA 572 |
| Chain | Residue | Details |
| F | GLU35 | metal ligand |
| F | GLU66 | metal ligand |
| F | HIS69 | metal ligand |
| F | GLU148 | metal ligand |
| F | GLU178 | proton acceptor, proton donor, proton shuttle (general acid/base) |
| F | HIS181 | metal ligand |
