1O7L

Molybdate-activated form of ModE from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
A	0003677	molecular_function	DNA binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0015689	biological_process	molybdate ion transport
A	0030151	molecular_function	molybdenum ion binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding
A	2000143	biological_process	negative regulation of DNA-templated transcription initiation
B	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
B	0003677	molecular_function	DNA binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0015689	biological_process	molybdate ion transport
B	0030151	molecular_function	molybdenum ion binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0046872	molecular_function	metal ion binding
B	2000143	biological_process	negative regulation of DNA-templated transcription initiation
C	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
C	0003677	molecular_function	DNA binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0015689	biological_process	molybdate ion transport
C	0030151	molecular_function	molybdenum ion binding
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0046872	molecular_function	metal ion binding
C	2000143	biological_process	negative regulation of DNA-templated transcription initiation
D	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
D	0003677	molecular_function	DNA binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0015689	biological_process	molybdate ion transport
D	0030151	molecular_function	molybdenum ion binding
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0046872	molecular_function	metal ion binding
D	2000143	biological_process	negative regulation of DNA-templated transcription initiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B1264

Chain	Residue
B	ALA214

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D1265

Chain	Residue
C	GLU215
D	ASP141
D	GLN144
D	MOO1264
D	HOH2004

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MOO A1263

Chain	Residue
A	LYS183
A	ALA184
A	PRO185
B	THR163
B	SER166
A	SER126
A	ALA127
A	ARG128

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MOO B1263

Chain	Residue
A	THR163
A	SER166
B	SER126
B	ALA127
B	ARG128
B	LYS183
B	ALA184
B	PRO185

---

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MOO C1262

Chain	Residue
C	SER126
C	ALA127
C	ARG128
C	LYS183
C	ALA184
C	PRO185
D	ILE162
D	THR163
D	SER166

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MOO D1263

Chain	Residue
C	ILE162
C	THR163
C	SER166
D	SER126
D	ALA127
D	ARG128
D	LYS183
D	ALA184
D	PRO185

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MOO D1264

Chain	Residue
B	HIS140
C	GLY213
C	ALA214
C	GLN216
D	ASP141
D	ASP142
D	VAL143
D	GLN144
D	CA1265

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	268
Details	Domain: {"description":"Mop 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01213","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	256
Details	Domain: {"description":"Mop 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01213","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	Region: {"description":"Required for dimer formation and molybdate binding"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11259434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12581638","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1H9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O7L","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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