1O4A
CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82197.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE 197 A 300 |
| Chain | Residue |
| A | ARG14 |
| A | THR74 |
| A | GLY95 |
| A | LEU96 |
| A | THR102 |
| A | VAL103 |
| A | PRO105 |
| A | THR106 |
| A | HOH336 |
| A | HOH375 |
| A | HOH426 |
| A | ARG34 |
| A | HOH431 |
| A | HOH432 |
| A | SER36 |
| A | GLU37 |
| A | THR38 |
| A | CYS44 |
| A | HIS60 |
| A | TYR61 |
| A | LYS62 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 97 |
| Details | Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P05480","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
