1O2Q
Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE CA A 247 |
| 鎖名 | 残基 |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH248 |
| A | HOH560 |
| site_id | AC2 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE SO4 A 260 |
| 鎖名 | 残基 |
| A | HOH271 |
| A | HOH727 |
| A | PRO173 |
| A | GLY174 |
| A | GLN240 |
| site_id | AC3 |
| 残基数 | 12 |
| 詳細 | BINDING SITE FOR RESIDUE 991 A 246 |
| 鎖名 | 残基 |
| A | HIS57 |
| A | ASP189 |
| A | SER190 |
| A | GLN192 |
| A | SER195 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | GLY226 |
| A | VAL227 |
| A | HOH705 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 220 |
| 詳細 | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| 鎖名 | 残基 | 詳細 |
| site_id | SWS_FT_FI2 |
| 残基数 | 3 |
| 詳細 | Active site: {"description":"Charge relay system"} |
| 鎖名 | 残基 | 詳細 |
| site_id | SWS_FT_FI3 |
| 残基数 | 7 |
| 詳細 | Binding site: {} |
| 鎖名 | 残基 | 詳細 |
CSAにおける酵素触媒機能の情報
| site_id | CSA1 |
| 残基数 | 2 |
| 詳細 | Annotated By Reference To The Literature 1a0j |
| 鎖名 | 残基 | 詳細 |
| A | ASP102 | |
| A | HIS57 |
| site_id | CSA2 |
| 残基数 | 2 |
| 詳細 | Annotated By Reference To The Literature 1a0j |
| 鎖名 | 残基 | 詳細 |
| A | SER195 | |
| A | GLY196 |
| site_id | CSA3 |
| 残基数 | 2 |
| 詳細 | Annotated By Reference To The Literature 1a0j |
| 鎖名 | 残基 | 詳細 |
| A | SER195 | |
| A | GLY193 |
| site_id | CSA4 |
| 残基数 | 3 |
| 詳細 | Annotated By Reference To The Literature 1a0j |
| 鎖名 | 残基 | 詳細 |
| A | ASP102 | |
| A | SER195 | |
| A | HIS57 |
| site_id | CSA5 |
| 残基数 | 4 |
| 詳細 | Annotated By Reference To The Literature 1a0j |
| 鎖名 | 残基 | 詳細 |
| A | ASP102 | |
| A | SER195 | |
| A | GLY193 | |
| A | HIS57 |
| site_id | CSA6 |
| 残基数 | 4 |
| 詳細 | Annotated By Reference To The Literature 1a0j |
| 鎖名 | 残基 | 詳細 |
| A | ASP102 | |
| A | SER195 | |
| A | HIS57 | |
| A | GLY196 |
