1O1E

MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000166	molecular_function	nucleotide binding
1	0000287	molecular_function	magnesium ion binding
1	0001725	cellular_component	stress fiber
1	0003785	molecular_function	actin monomer binding
1	0005509	molecular_function	calcium ion binding
1	0005515	molecular_function	protein binding
1	0005523	molecular_function	tropomyosin binding
1	0005524	molecular_function	ATP binding
1	0005737	cellular_component	cytoplasm
1	0005856	cellular_component	cytoskeleton
1	0005865	cellular_component	striated muscle thin filament
1	0005884	cellular_component	actin filament
1	0010628	biological_process	positive regulation of gene expression
1	0016787	molecular_function	hydrolase activity
1	0019904	molecular_function	protein domain specific binding
1	0030027	cellular_component	lamellipodium
1	0030041	biological_process	actin filament polymerization
1	0030175	cellular_component	filopodium
1	0030240	biological_process	skeletal muscle thin filament assembly
1	0031013	molecular_function	troponin I binding
1	0031432	molecular_function	titin binding
1	0031941	cellular_component	filamentous actin
1	0032036	molecular_function	myosin heavy chain binding
1	0032432	cellular_component	actin filament bundle
1	0042802	molecular_function	identical protein binding
1	0044297	cellular_component	cell body
1	0048306	molecular_function	calcium-dependent protein binding
1	0048741	biological_process	skeletal muscle fiber development
1	0051017	biological_process	actin filament bundle assembly
1	0090131	biological_process	mesenchyme migration
1	0098723	cellular_component	skeletal muscle myofibril
1	0140660	molecular_function	cytoskeletal motor activator activity
2	0000166	molecular_function	nucleotide binding
2	0000287	molecular_function	magnesium ion binding
2	0001725	cellular_component	stress fiber
2	0003785	molecular_function	actin monomer binding
2	0005509	molecular_function	calcium ion binding
2	0005515	molecular_function	protein binding
2	0005523	molecular_function	tropomyosin binding
2	0005524	molecular_function	ATP binding
2	0005737	cellular_component	cytoplasm
2	0005856	cellular_component	cytoskeleton
2	0005865	cellular_component	striated muscle thin filament
2	0005884	cellular_component	actin filament
2	0010628	biological_process	positive regulation of gene expression
2	0016787	molecular_function	hydrolase activity
2	0019904	molecular_function	protein domain specific binding
2	0030027	cellular_component	lamellipodium
2	0030041	biological_process	actin filament polymerization
2	0030175	cellular_component	filopodium
2	0030240	biological_process	skeletal muscle thin filament assembly
2	0031013	molecular_function	troponin I binding
2	0031432	molecular_function	titin binding
2	0031941	cellular_component	filamentous actin
2	0032036	molecular_function	myosin heavy chain binding
2	0032432	cellular_component	actin filament bundle
2	0042802	molecular_function	identical protein binding
2	0044297	cellular_component	cell body
2	0048306	molecular_function	calcium-dependent protein binding
2	0048741	biological_process	skeletal muscle fiber development
2	0051017	biological_process	actin filament bundle assembly
2	0090131	biological_process	mesenchyme migration
2	0098723	cellular_component	skeletal muscle myofibril
2	0140660	molecular_function	cytoskeletal motor activator activity
3	0000166	molecular_function	nucleotide binding
3	0000287	molecular_function	magnesium ion binding
3	0001725	cellular_component	stress fiber
3	0003785	molecular_function	actin monomer binding
3	0005509	molecular_function	calcium ion binding
3	0005515	molecular_function	protein binding
3	0005523	molecular_function	tropomyosin binding
3	0005524	molecular_function	ATP binding
3	0005737	cellular_component	cytoplasm
3	0005856	cellular_component	cytoskeleton
3	0005865	cellular_component	striated muscle thin filament
3	0005884	cellular_component	actin filament
3	0010628	biological_process	positive regulation of gene expression
3	0016787	molecular_function	hydrolase activity
3	0019904	molecular_function	protein domain specific binding
3	0030027	cellular_component	lamellipodium
3	0030041	biological_process	actin filament polymerization
3	0030175	cellular_component	filopodium
3	0030240	biological_process	skeletal muscle thin filament assembly
3	0031013	molecular_function	troponin I binding
3	0031432	molecular_function	titin binding
3	0031941	cellular_component	filamentous actin
3	0032036	molecular_function	myosin heavy chain binding
3	0032432	cellular_component	actin filament bundle
3	0042802	molecular_function	identical protein binding
3	0044297	cellular_component	cell body
3	0048306	molecular_function	calcium-dependent protein binding
3	0048741	biological_process	skeletal muscle fiber development
3	0051017	biological_process	actin filament bundle assembly
3	0090131	biological_process	mesenchyme migration
3	0098723	cellular_component	skeletal muscle myofibril
3	0140660	molecular_function	cytoskeletal motor activator activity
4	0000166	molecular_function	nucleotide binding
4	0000287	molecular_function	magnesium ion binding
4	0001725	cellular_component	stress fiber
4	0003785	molecular_function	actin monomer binding
4	0005509	molecular_function	calcium ion binding
4	0005515	molecular_function	protein binding
4	0005523	molecular_function	tropomyosin binding
4	0005524	molecular_function	ATP binding
4	0005737	cellular_component	cytoplasm
4	0005856	cellular_component	cytoskeleton
4	0005865	cellular_component	striated muscle thin filament
4	0005884	cellular_component	actin filament
4	0010628	biological_process	positive regulation of gene expression
4	0016787	molecular_function	hydrolase activity
4	0019904	molecular_function	protein domain specific binding
4	0030027	cellular_component	lamellipodium
4	0030041	biological_process	actin filament polymerization
4	0030175	cellular_component	filopodium
4	0030240	biological_process	skeletal muscle thin filament assembly
4	0031013	molecular_function	troponin I binding
4	0031432	molecular_function	titin binding
4	0031941	cellular_component	filamentous actin
4	0032036	molecular_function	myosin heavy chain binding
4	0032432	cellular_component	actin filament bundle
4	0042802	molecular_function	identical protein binding
4	0044297	cellular_component	cell body
4	0048306	molecular_function	calcium-dependent protein binding
4	0048741	biological_process	skeletal muscle fiber development
4	0051017	biological_process	actin filament bundle assembly
4	0090131	biological_process	mesenchyme migration
4	0098723	cellular_component	skeletal muscle myofibril
4	0140660	molecular_function	cytoskeletal motor activator activity
5	0000166	molecular_function	nucleotide binding
5	0000287	molecular_function	magnesium ion binding
5	0001725	cellular_component	stress fiber
5	0003785	molecular_function	actin monomer binding
5	0005509	molecular_function	calcium ion binding
5	0005515	molecular_function	protein binding
5	0005523	molecular_function	tropomyosin binding
5	0005524	molecular_function	ATP binding
5	0005737	cellular_component	cytoplasm
5	0005856	cellular_component	cytoskeleton
5	0005865	cellular_component	striated muscle thin filament
5	0005884	cellular_component	actin filament
5	0010628	biological_process	positive regulation of gene expression
5	0016787	molecular_function	hydrolase activity
5	0019904	molecular_function	protein domain specific binding
5	0030027	cellular_component	lamellipodium
5	0030041	biological_process	actin filament polymerization
5	0030175	cellular_component	filopodium
5	0030240	biological_process	skeletal muscle thin filament assembly
5	0031013	molecular_function	troponin I binding
5	0031432	molecular_function	titin binding
5	0031941	cellular_component	filamentous actin
5	0032036	molecular_function	myosin heavy chain binding
5	0032432	cellular_component	actin filament bundle
5	0042802	molecular_function	identical protein binding
5	0044297	cellular_component	cell body
5	0048306	molecular_function	calcium-dependent protein binding
5	0048741	biological_process	skeletal muscle fiber development
5	0051017	biological_process	actin filament bundle assembly
5	0090131	biological_process	mesenchyme migration
5	0098723	cellular_component	skeletal muscle myofibril
5	0140660	molecular_function	cytoskeletal motor activator activity
6	0000166	molecular_function	nucleotide binding
6	0000287	molecular_function	magnesium ion binding
6	0001725	cellular_component	stress fiber
6	0003785	molecular_function	actin monomer binding
6	0005509	molecular_function	calcium ion binding
6	0005515	molecular_function	protein binding
6	0005523	molecular_function	tropomyosin binding
6	0005524	molecular_function	ATP binding
6	0005737	cellular_component	cytoplasm
6	0005856	cellular_component	cytoskeleton
6	0005865	cellular_component	striated muscle thin filament
6	0005884	cellular_component	actin filament
6	0010628	biological_process	positive regulation of gene expression
6	0016787	molecular_function	hydrolase activity
6	0019904	molecular_function	protein domain specific binding
6	0030027	cellular_component	lamellipodium
6	0030041	biological_process	actin filament polymerization
6	0030175	cellular_component	filopodium
6	0030240	biological_process	skeletal muscle thin filament assembly
6	0031013	molecular_function	troponin I binding
6	0031432	molecular_function	titin binding
6	0031941	cellular_component	filamentous actin
6	0032036	molecular_function	myosin heavy chain binding
6	0032432	cellular_component	actin filament bundle
6	0042802	molecular_function	identical protein binding
6	0044297	cellular_component	cell body
6	0048306	molecular_function	calcium-dependent protein binding
6	0048741	biological_process	skeletal muscle fiber development
6	0051017	biological_process	actin filament bundle assembly
6	0090131	biological_process	mesenchyme migration
6	0098723	cellular_component	skeletal muscle myofibril
6	0140660	molecular_function	cytoskeletal motor activator activity
7	0000166	molecular_function	nucleotide binding
7	0000287	molecular_function	magnesium ion binding
7	0001725	cellular_component	stress fiber
7	0003785	molecular_function	actin monomer binding
7	0005509	molecular_function	calcium ion binding
7	0005515	molecular_function	protein binding
7	0005523	molecular_function	tropomyosin binding
7	0005524	molecular_function	ATP binding
7	0005737	cellular_component	cytoplasm
7	0005856	cellular_component	cytoskeleton
7	0005865	cellular_component	striated muscle thin filament
7	0005884	cellular_component	actin filament
7	0010628	biological_process	positive regulation of gene expression
7	0016787	molecular_function	hydrolase activity
7	0019904	molecular_function	protein domain specific binding
7	0030027	cellular_component	lamellipodium
7	0030041	biological_process	actin filament polymerization
7	0030175	cellular_component	filopodium
7	0030240	biological_process	skeletal muscle thin filament assembly
7	0031013	molecular_function	troponin I binding
7	0031432	molecular_function	titin binding
7	0031941	cellular_component	filamentous actin
7	0032036	molecular_function	myosin heavy chain binding
7	0032432	cellular_component	actin filament bundle
7	0042802	molecular_function	identical protein binding
7	0044297	cellular_component	cell body
7	0048306	molecular_function	calcium-dependent protein binding
7	0048741	biological_process	skeletal muscle fiber development
7	0051017	biological_process	actin filament bundle assembly
7	0090131	biological_process	mesenchyme migration
7	0098723	cellular_component	skeletal muscle myofibril
7	0140660	molecular_function	cytoskeletal motor activator activity
8	0000166	molecular_function	nucleotide binding
8	0000287	molecular_function	magnesium ion binding
8	0001725	cellular_component	stress fiber
8	0003785	molecular_function	actin monomer binding
8	0005509	molecular_function	calcium ion binding
8	0005515	molecular_function	protein binding
8	0005523	molecular_function	tropomyosin binding
8	0005524	molecular_function	ATP binding
8	0005737	cellular_component	cytoplasm
8	0005856	cellular_component	cytoskeleton
8	0005865	cellular_component	striated muscle thin filament
8	0005884	cellular_component	actin filament
8	0010628	biological_process	positive regulation of gene expression
8	0016787	molecular_function	hydrolase activity
8	0019904	molecular_function	protein domain specific binding
8	0030027	cellular_component	lamellipodium
8	0030041	biological_process	actin filament polymerization
8	0030175	cellular_component	filopodium
8	0030240	biological_process	skeletal muscle thin filament assembly
8	0031013	molecular_function	troponin I binding
8	0031432	molecular_function	titin binding
8	0031941	cellular_component	filamentous actin
8	0032036	molecular_function	myosin heavy chain binding
8	0032432	cellular_component	actin filament bundle
8	0042802	molecular_function	identical protein binding
8	0044297	cellular_component	cell body
8	0048306	molecular_function	calcium-dependent protein binding
8	0048741	biological_process	skeletal muscle fiber development
8	0051017	biological_process	actin filament bundle assembly
8	0090131	biological_process	mesenchyme migration
8	0098723	cellular_component	skeletal muscle myofibril
8	0140660	molecular_function	cytoskeletal motor activator activity
9	0000166	molecular_function	nucleotide binding
9	0000287	molecular_function	magnesium ion binding
9	0001725	cellular_component	stress fiber
9	0003785	molecular_function	actin monomer binding
9	0005509	molecular_function	calcium ion binding
9	0005515	molecular_function	protein binding
9	0005523	molecular_function	tropomyosin binding
9	0005524	molecular_function	ATP binding
9	0005737	cellular_component	cytoplasm
9	0005856	cellular_component	cytoskeleton
9	0005865	cellular_component	striated muscle thin filament
9	0005884	cellular_component	actin filament
9	0010628	biological_process	positive regulation of gene expression
9	0016787	molecular_function	hydrolase activity
9	0019904	molecular_function	protein domain specific binding
9	0030027	cellular_component	lamellipodium
9	0030041	biological_process	actin filament polymerization
9	0030175	cellular_component	filopodium
9	0030240	biological_process	skeletal muscle thin filament assembly
9	0031013	molecular_function	troponin I binding
9	0031432	molecular_function	titin binding
9	0031941	cellular_component	filamentous actin
9	0032036	molecular_function	myosin heavy chain binding
9	0032432	cellular_component	actin filament bundle
9	0042802	molecular_function	identical protein binding
9	0044297	cellular_component	cell body
9	0048306	molecular_function	calcium-dependent protein binding
9	0048741	biological_process	skeletal muscle fiber development
9	0051017	biological_process	actin filament bundle assembly
9	0090131	biological_process	mesenchyme migration
9	0098723	cellular_component	skeletal muscle myofibril
9	0140660	molecular_function	cytoskeletal motor activator activity
A	0003774	molecular_function	cytoskeletal motor activity
A	0005524	molecular_function	ATP binding
A	0016459	cellular_component	myosin complex
A	0051015	molecular_function	actin filament binding
B	0005509	molecular_function	calcium ion binding
C	0005509	molecular_function	calcium ion binding
C	0016459	cellular_component	myosin complex
C	0016460	cellular_component	myosin II complex
C	0043292	cellular_component	contractile muscle fiber
D	0003774	molecular_function	cytoskeletal motor activity
D	0005524	molecular_function	ATP binding
D	0016459	cellular_component	myosin complex
D	0051015	molecular_function	actin filament binding
E	0005509	molecular_function	calcium ion binding
F	0005509	molecular_function	calcium ion binding
F	0016459	cellular_component	myosin complex
F	0016460	cellular_component	myosin II complex
F	0043292	cellular_component	contractile muscle fiber
G	0003774	molecular_function	cytoskeletal motor activity
G	0005524	molecular_function	ATP binding
G	0016459	cellular_component	myosin complex
G	0051015	molecular_function	actin filament binding
H	0005509	molecular_function	calcium ion binding
I	0005509	molecular_function	calcium ion binding
I	0016459	cellular_component	myosin complex
I	0016460	cellular_component	myosin II complex
I	0043292	cellular_component	contractile muscle fiber
J	0003774	molecular_function	cytoskeletal motor activity
J	0005524	molecular_function	ATP binding
J	0016459	cellular_component	myosin complex
J	0051015	molecular_function	actin filament binding
K	0005509	molecular_function	calcium ion binding
L	0005509	molecular_function	calcium ion binding
L	0016459	cellular_component	myosin complex
L	0016460	cellular_component	myosin II complex
L	0043292	cellular_component	contractile muscle fiber
M	0003774	molecular_function	cytoskeletal motor activity
M	0005524	molecular_function	ATP binding
M	0016459	cellular_component	myosin complex
M	0051015	molecular_function	actin filament binding
N	0005509	molecular_function	calcium ion binding
O	0005509	molecular_function	calcium ion binding
O	0016459	cellular_component	myosin complex
O	0016460	cellular_component	myosin II complex
O	0043292	cellular_component	contractile muscle fiber
P	0003774	molecular_function	cytoskeletal motor activity
P	0005524	molecular_function	ATP binding
P	0016459	cellular_component	myosin complex
P	0051015	molecular_function	actin filament binding
Q	0005509	molecular_function	calcium ion binding
R	0005509	molecular_function	calcium ion binding
R	0016459	cellular_component	myosin complex
R	0016460	cellular_component	myosin II complex
R	0043292	cellular_component	contractile muscle fiber
V	0000166	molecular_function	nucleotide binding
V	0000287	molecular_function	magnesium ion binding
V	0001725	cellular_component	stress fiber
V	0003785	molecular_function	actin monomer binding
V	0005509	molecular_function	calcium ion binding
V	0005515	molecular_function	protein binding
V	0005523	molecular_function	tropomyosin binding
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0005856	cellular_component	cytoskeleton
V	0005865	cellular_component	striated muscle thin filament
V	0005884	cellular_component	actin filament
V	0010628	biological_process	positive regulation of gene expression
V	0016787	molecular_function	hydrolase activity
V	0019904	molecular_function	protein domain specific binding
V	0030027	cellular_component	lamellipodium
V	0030041	biological_process	actin filament polymerization
V	0030175	cellular_component	filopodium
V	0030240	biological_process	skeletal muscle thin filament assembly
V	0031013	molecular_function	troponin I binding
V	0031432	molecular_function	titin binding
V	0031941	cellular_component	filamentous actin
V	0032036	molecular_function	myosin heavy chain binding
V	0032432	cellular_component	actin filament bundle
V	0042802	molecular_function	identical protein binding
V	0044297	cellular_component	cell body
V	0048306	molecular_function	calcium-dependent protein binding
V	0048741	biological_process	skeletal muscle fiber development
V	0051017	biological_process	actin filament bundle assembly
V	0090131	biological_process	mesenchyme migration
V	0098723	cellular_component	skeletal muscle myofibril
V	0140660	molecular_function	cytoskeletal motor activator activity
W	0000166	molecular_function	nucleotide binding
W	0000287	molecular_function	magnesium ion binding
W	0001725	cellular_component	stress fiber
W	0003785	molecular_function	actin monomer binding
W	0005509	molecular_function	calcium ion binding
W	0005515	molecular_function	protein binding
W	0005523	molecular_function	tropomyosin binding
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0005856	cellular_component	cytoskeleton
W	0005865	cellular_component	striated muscle thin filament
W	0005884	cellular_component	actin filament
W	0010628	biological_process	positive regulation of gene expression
W	0016787	molecular_function	hydrolase activity
W	0019904	molecular_function	protein domain specific binding
W	0030027	cellular_component	lamellipodium
W	0030041	biological_process	actin filament polymerization
W	0030175	cellular_component	filopodium
W	0030240	biological_process	skeletal muscle thin filament assembly
W	0031013	molecular_function	troponin I binding
W	0031432	molecular_function	titin binding
W	0031941	cellular_component	filamentous actin
W	0032036	molecular_function	myosin heavy chain binding
W	0032432	cellular_component	actin filament bundle
W	0042802	molecular_function	identical protein binding
W	0044297	cellular_component	cell body
W	0048306	molecular_function	calcium-dependent protein binding
W	0048741	biological_process	skeletal muscle fiber development
W	0051017	biological_process	actin filament bundle assembly
W	0090131	biological_process	mesenchyme migration
W	0098723	cellular_component	skeletal muscle myofibril
W	0140660	molecular_function	cytoskeletal motor activator activity
X	0000166	molecular_function	nucleotide binding
X	0000287	molecular_function	magnesium ion binding
X	0001725	cellular_component	stress fiber
X	0003785	molecular_function	actin monomer binding
X	0005509	molecular_function	calcium ion binding
X	0005515	molecular_function	protein binding
X	0005523	molecular_function	tropomyosin binding
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0005856	cellular_component	cytoskeleton
X	0005865	cellular_component	striated muscle thin filament
X	0005884	cellular_component	actin filament
X	0010628	biological_process	positive regulation of gene expression
X	0016787	molecular_function	hydrolase activity
X	0019904	molecular_function	protein domain specific binding
X	0030027	cellular_component	lamellipodium
X	0030041	biological_process	actin filament polymerization
X	0030175	cellular_component	filopodium
X	0030240	biological_process	skeletal muscle thin filament assembly
X	0031013	molecular_function	troponin I binding
X	0031432	molecular_function	titin binding
X	0031941	cellular_component	filamentous actin
X	0032036	molecular_function	myosin heavy chain binding
X	0032432	cellular_component	actin filament bundle
X	0042802	molecular_function	identical protein binding
X	0044297	cellular_component	cell body
X	0048306	molecular_function	calcium-dependent protein binding
X	0048741	biological_process	skeletal muscle fiber development
X	0051017	biological_process	actin filament bundle assembly
X	0090131	biological_process	mesenchyme migration
X	0098723	cellular_component	skeletal muscle myofibril
X	0140660	molecular_function	cytoskeletal motor activator activity
Y	0000166	molecular_function	nucleotide binding
Y	0000287	molecular_function	magnesium ion binding
Y	0001725	cellular_component	stress fiber
Y	0003785	molecular_function	actin monomer binding
Y	0005509	molecular_function	calcium ion binding
Y	0005515	molecular_function	protein binding
Y	0005523	molecular_function	tropomyosin binding
Y	0005524	molecular_function	ATP binding
Y	0005737	cellular_component	cytoplasm
Y	0005856	cellular_component	cytoskeleton
Y	0005865	cellular_component	striated muscle thin filament
Y	0005884	cellular_component	actin filament
Y	0010628	biological_process	positive regulation of gene expression
Y	0016787	molecular_function	hydrolase activity
Y	0019904	molecular_function	protein domain specific binding
Y	0030027	cellular_component	lamellipodium
Y	0030041	biological_process	actin filament polymerization
Y	0030175	cellular_component	filopodium
Y	0030240	biological_process	skeletal muscle thin filament assembly
Y	0031013	molecular_function	troponin I binding
Y	0031432	molecular_function	titin binding
Y	0031941	cellular_component	filamentous actin
Y	0032036	molecular_function	myosin heavy chain binding
Y	0032432	cellular_component	actin filament bundle
Y	0042802	molecular_function	identical protein binding
Y	0044297	cellular_component	cell body
Y	0048306	molecular_function	calcium-dependent protein binding
Y	0048741	biological_process	skeletal muscle fiber development
Y	0051017	biological_process	actin filament bundle assembly
Y	0090131	biological_process	mesenchyme migration
Y	0098723	cellular_component	skeletal muscle myofibril
Y	0140660	molecular_function	cytoskeletal motor activator activity
Z	0000166	molecular_function	nucleotide binding
Z	0000287	molecular_function	magnesium ion binding
Z	0001725	cellular_component	stress fiber
Z	0003785	molecular_function	actin monomer binding
Z	0005509	molecular_function	calcium ion binding
Z	0005515	molecular_function	protein binding
Z	0005523	molecular_function	tropomyosin binding
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005856	cellular_component	cytoskeleton
Z	0005865	cellular_component	striated muscle thin filament
Z	0005884	cellular_component	actin filament
Z	0010628	biological_process	positive regulation of gene expression
Z	0016787	molecular_function	hydrolase activity
Z	0019904	molecular_function	protein domain specific binding
Z	0030027	cellular_component	lamellipodium
Z	0030041	biological_process	actin filament polymerization
Z	0030175	cellular_component	filopodium
Z	0030240	biological_process	skeletal muscle thin filament assembly
Z	0031013	molecular_function	troponin I binding
Z	0031432	molecular_function	titin binding
Z	0031941	cellular_component	filamentous actin
Z	0032036	molecular_function	myosin heavy chain binding
Z	0032432	cellular_component	actin filament bundle
Z	0042802	molecular_function	identical protein binding
Z	0044297	cellular_component	cell body
Z	0048306	molecular_function	calcium-dependent protein binding
Z	0048741	biological_process	skeletal muscle fiber development
Z	0051017	biological_process	actin filament bundle assembly
Z	0090131	biological_process	mesenchyme migration
Z	0098723	cellular_component	skeletal muscle myofibril
Z	0140660	molecular_function	cytoskeletal motor activator activity

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DQNADGIIDkdDL

Chain	Residue	Details
B	ASP35-LEU47

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site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
9	TYR53-GLY63

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site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WITKqEYDE

Chain	Residue	Details
9	TRP356-GLU364

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site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
9	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	42
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"3467365","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"3467365","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	210
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	420
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	210
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	192
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	350
Details	Region: {"description":"Interaction with alpha-actinin","evidences":[{"source":"PubMed","id":"8449927","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	14
Details	Modified residue: {"description":"N-acetylaspartate; in Actin, alpha skeletal muscle","evidences":[{"source":"PubMed","id":"1150665","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	28
Details	Modified residue: {"description":"Methionine (R)-sulfoxide","evidences":[{"source":"UniProtKB","id":"P68134","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	14
Details	Modified residue: {"description":"N6-malonyllysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	14
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"1150665","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16905096","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"213279","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2395459","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"499690","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ATN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NWK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	14
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P68133","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	14
Details	Modified residue: {"description":"ADP-ribosylarginine; by SpvB","evidences":[{"source":"PubMed","id":"16905096","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
A	GLY466
A	GLY182
A	GLU468
A	ASN240

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
D	GLY466
D	GLY182
D	GLU468
D	ASN240

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
G	GLY466
G	GLY182
G	GLU468
G	ASN240

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
J	GLY466
J	GLY182
J	GLU468
J	ASN240

---

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
M	GLY466
M	GLY182
M	GLU468
M	ASN240

---

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
P	GLY466
P	GLY182
P	GLU468
P	ASN240

---