1NZB

Crystal structure of wild type Cre recombinase-loxP synapse

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006310	biological_process	DNA recombination
A	0015074	biological_process	DNA integration
B	0003677	molecular_function	DNA binding
B	0006310	biological_process	DNA recombination
B	0015074	biological_process	DNA integration
E	0003677	molecular_function	DNA binding
E	0006310	biological_process	DNA recombination
E	0015074	biological_process	DNA integration
F	0003677	molecular_function	DNA binding
F	0006310	biological_process	DNA recombination
F	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 5301

Chain	Residue
A	HIS40
C	DT125

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 5302

Chain	Residue
A	HIS269

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 5304

Chain	Residue
A	GLN156
A	ARG159
A	ASN160
D	DC106

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 5305

Chain	Residue
D	DT107

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG G 5306

Chain	Residue
G	DG117

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 5308

Chain	Residue
C	DG117

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 5309

Chain	Residue
F	THR87
F	HIS91
G	DA112

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 5310

Chain	Residue
D	DA105

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246

Chain	Residue	Details
A	ARG173
E	HIS289
E	ARG292
E	TRP315
F	ARG173
F	HIS289
F	ARG292
F	TRP315
A	HIS289
A	ARG292
A	TRP315
B	ARG173
B	HIS289
B	ARG292
B	TRP315
E	ARG173

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: O-(3'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01246

Chain	Residue	Details
A	TYR324
B	TYR324
E	TYR324
F	TYR324

---