1NYJ
The closed state structure of M2 protein H+ channel by solid state NMR spectroscopy
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015078 | molecular_function | proton transmembrane transporter activity |
| A | 0033644 | cellular_component | host cell membrane |
| A | 0055036 | cellular_component | virion membrane |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0015078 | molecular_function | proton transmembrane transporter activity |
| B | 0033644 | cellular_component | host cell membrane |
| B | 0055036 | cellular_component | virion membrane |
| B | 1902600 | biological_process | proton transmembrane transport |
| C | 0015078 | molecular_function | proton transmembrane transporter activity |
| C | 0033644 | cellular_component | host cell membrane |
| C | 0055036 | cellular_component | virion membrane |
| C | 1902600 | biological_process | proton transmembrane transport |
| D | 0015078 | molecular_function | proton transmembrane transporter activity |
| D | 0033644 | cellular_component | host cell membrane |
| D | 0055036 | cellular_component | virion membrane |
| D | 1902600 | biological_process | proton transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | TRANSMEM: Helical; Signal-anchor for type III membrane protein => ECO:0000255|HAMAP-Rule:MF_04069 |
| Chain | Residue | Details |
| A | SER2-LEU22 | |
| B | SER2-LEU22 | |
| C | SER2-LEU22 | |
| D | SER2-LEU22 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter => ECO:0000255|HAMAP-Rule:MF_04069 |
| Chain | Residue | Details |
| A | HIS16 | |
| B | HIS16 | |
| C | HIS16 | |
| D | HIS16 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Seems to be involved in pH gating => ECO:0000255|HAMAP-Rule:MF_04069 |
| Chain | Residue | Details |
| A | TRP20 | |
| B | TRP20 | |
| C | TRP20 | |
| D | TRP20 |
