Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 319 |
Chain | Residue |
A | ASP139 |
A | GLU178 |
A | ASP186 |
A | GLU188 |
A | GLU191 |
A | HOH346 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 320 |
Chain | Residue |
A | GLU178 |
A | ASN184 |
A | ASP186 |
A | GLU191 |
A | HOH339 |
A | HOH357 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 321 |
Chain | Residue |
A | ASP58 |
A | ASP60 |
A | VAL62 |
A | HOH327 |
A | HOH377 |
A | HOH396 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 322 |
Chain | Residue |
A | TYR194 |
A | THR195 |
A | LYS198 |
A | ASP201 |
A | HOH349 |
A | HOH380 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 323 |
Chain | Residue |
A | HIS143 |
A | HIS147 |
A | GLU167 |
A | HOH326 |
site_id | CA1 |
Number of Residues | 6 |
Details | |
Chain | Residue |
A | HOH346 |
A | ASP139 |
A | GLU178 |
A | ASP186 |
A | GLU188 |
A | GLU191 |
site_id | CA2 |
Number of Residues | 6 |
Details | |
Chain | Residue |
A | GLU178 |
A | ASN184 |
A | ASP186 |
A | GLU191 |
A | HOH357 |
A | HOH339 |
site_id | CA3 |
Number of Residues | 6 |
Details | |
Chain | Residue |
A | ASP58 |
A | ASP60 |
A | VAL62 |
A | HOH327 |
A | HOH396 |
A | HOH377 |
site_id | CA4 |
Number of Residues | 6 |
Details | |
Chain | Residue |
A | TYR194 |
A | THR195 |
A | LYS198 |
A | ASP201 |
A | HOH349 |
A | HOH380 |
site_id | ZIN |
Number of Residues | 4 |
Details | |
Chain | Residue |
A | HIS143 |
A | HIS147 |
A | GLU167 |
A | HOH326 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VIGHELTHAV |
Chain | Residue | Details |
A | VAL140-VAL149 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | GLU144 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
A | HIS232 | |
Chain | Residue | Details |
A | ASP58 | |
A | ASP60 | |
A | ASP139 | |
A | GLU178 | |
A | ASP186 | |
A | GLU191 | |
A | THR195 | |
A | ASP201 | |
site_id | SWS_FT_FI4 |
Number of Residues | 5 |
Details | BINDING: |
Chain | Residue | Details |
A | VAL62 | |
A | ASN184 | |
A | GLU188 | |
A | TYR194 | |
A | LYS198 | |
Chain | Residue | Details |
A | HIS143 | |
A | HIS147 | |
A | GLU167 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1tlp |
Chain | Residue | Details |
A | GLU144 | |
A | HIS232 | |