1NNR
Crystal structure of a probable fosfomycin resistance protein (PA1129) from Pseudomonas aeruginosa with sulfate present in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 201 |
| Chain | Residue |
| A | HIS7 |
| B | HIS64 |
| B | GLU110 |
| B | SO4301 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 202 |
| Chain | Residue |
| A | HIS64 |
| A | GLU110 |
| A | SO4302 |
| B | HIS7 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 301 |
| Chain | Residue |
| B | SER94 |
| B | TYR100 |
| B | GLU110 |
| B | ARG119 |
| B | MN201 |
| B | HOH314 |
| B | HOH337 |
| B | TYR62 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | TYR62 |
| A | HIS64 |
| A | SER94 |
| A | TYR100 |
| A | ARG119 |
| A | MN202 |
| A | HOH315 |
| A | HOH319 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|PROSITE-ProRule:PRU01163 |
| Chain | Residue | Details |
| A | GLU110 | |
| B | GLU110 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01163, ECO:0000269|PubMed:12224946, ECO:0007744|PDB:1LQK, ECO:0007744|PDB:1LQP, ECO:0007744|PDB:1NKI, ECO:0007744|PDB:1NNR |
| Chain | Residue | Details |
| A | HIS7 | |
| A | GLU110 | |
| B | HIS7 | |
| B | HIS64 | |
| B | GLU110 | |
| A | HIS64 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01163 |
| Chain | Residue | Details |
| A | GLU41 | |
| B | GLU41 |
