Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008379 | molecular_function | thioredoxin peroxidase activity |
| A | 0016209 | molecular_function | antioxidant activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008379 | molecular_function | thioredoxin peroxidase activity |
| B | 0016209 | molecular_function | antioxidant activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | LYS21 |
| A | VAL113 |
| A | GLY114 |
| A | LYS122 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | ARG17 |
| A | ASN144 |
| B | PRO47 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 503 |
| Chain | Residue |
| B | GLY179 |
| B | ASP20 |
| B | PRO178 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 504 |
| Chain | Residue |
| A | ASP24 |
| A | THR26 |
| A | ASP117 |
| B | ARG15 |
Functional Information from PROSITE/UniProt
| site_id | PS00195 |
| Number of Residues | 17 |
| Details | GLUTAREDOXIN_1 Glutaredoxin active site. IFtkpgCPFCakAkqlL |
| Chain | Residue | Details |
| A | ILE174-LEU190 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Cysteine sulfenic acid (-SOH) intermediate; for peroxiredoxin activity","evidences":[{"source":"PubMed","id":"12606554","evidenceCode":"ECO:0000305"}]} |
