1NKI
CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN A (FOSA) CONTAINING BOUND PHOSPHONOFORMATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K B 3001 |
| Chain | Residue |
| B | ASN92 |
| B | SER94 |
| B | GLU95 |
| B | GLY96 |
| B | SER98 |
| B | HIS112 |
| B | HOH9375 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K A 3002 |
| Chain | Residue |
| A | GLU95 |
| A | GLY96 |
| A | SER98 |
| A | HIS112 |
| A | HOH9366 |
| A | ASN92 |
| A | SER94 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 4003 |
| Chain | Residue |
| A | HIS7 |
| B | HIS64 |
| B | GLU110 |
| B | PPF5002 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 4004 |
| Chain | Residue |
| A | HIS64 |
| A | GLU110 |
| A | PPF5001 |
| B | HIS7 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PPF A 5001 |
| Chain | Residue |
| A | TYR62 |
| A | HIS64 |
| A | SER94 |
| A | TYR100 |
| A | GLU110 |
| A | ARG119 |
| A | MN4004 |
| A | HOH9049 |
| A | HOH9122 |
| A | HOH9146 |
| A | HOH9300 |
| A | HOH9366 |
| B | HIS7 |
| B | THR9 |
| B | CYS48 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PPF B 5002 |
| Chain | Residue |
| A | HIS7 |
| A | THR9 |
| A | CYS48 |
| A | HOH9038 |
| B | TYR62 |
| B | HIS64 |
| B | SER94 |
| B | TYR100 |
| B | GLU110 |
| B | ARG119 |
| B | MN4003 |
| B | HOH9048 |
| B | HOH9158 |
| B | HOH9351 |
| B | HOH9375 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"VOC","evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12224946","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NKI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NNR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| A | GLU110 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| B | GLU110 |
