Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 6001 |
| Chain | Residue |
| A | TRP42 |
| A | PRO44 |
| A | ARG57 |
| A | HOH6087 |
| B | GLU34 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 6002 |
| Chain | Residue |
| B | HOH6070 |
| B | HOH6106 |
| A | HOH6014 |
| B | GLN2 |
| B | ARG41 |
| B | ASN98 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BME A 5001 |
| Chain | Residue |
| A | VAL11 |
| A | THR12 |
| A | CYS67 |
| B | GLN7 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME B 5002 |
| Chain | Residue |
| B | THR12 |
| B | CYS67 |
| B | HOH6105 |
| site_id | AC5 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR CHAIN I OF PEPTIDOMIMETIC INHIBITOR KI2-PHE-GLU-GLU-NH2 |
| Chain | Residue |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | VAL82 |
| A | ILE84 |
| A | HOH6010 |
| A | HOH6015 |
| B | ARG8 |
| B | LEU23 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP30 |
| B | VAL32 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | VAL82 |
| B | ILE84 |
| I | HOH6 |
| I | HOH7 |
| I | HOH8 |
| I | HOH10 |
| site_id | AC6 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR CHAIN J OF PEPTIDOMIMETIC INHIBITOR KI2-PHE-GLU-GLU-NH2 |
| Chain | Residue |
| A | THR4 |
| A | TRP6 |
| A | PRO39 |
| A | GLY40 |
| A | ARG41 |
| A | HOH6064 |
| B | LYS14 |
| B | PRO44 |
| B | LYS45 |
| B | LYS55 |
| B | VAL56 |
| B | ARG57 |
| B | CYS67 |
| B | GLY68 |
| B | GLN92 |
| B | ILE93 |
| B | GLY94 |
| B | HOH6030 |
| B | HOH6034 |
| B | HOH6052 |
| B | HOH6079 |
| B | HOH6085 |
| B | HOH6115 |
| J | HOH8 |
| J | HOH22 |
| J | HOH93 |
| J | HOH152 |
| J | HOH177 |
| J | HOH225 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE64 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE64 | |
