1NGL
HUMAN NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (HNGAL), REGULARISED AVERAGE NMR STRUCTURE
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005506 | molecular_function | iron ion binding |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006826 | biological_process | iron ion transport |
A | 0006915 | biological_process | apoptotic process |
A | 0015891 | biological_process | siderophore transport |
A | 0031410 | cellular_component | cytoplasmic vesicle |
A | 0035580 | cellular_component | specific granule lumen |
A | 0036094 | molecular_function | small molecule binding |
A | 0042742 | biological_process | defense response to bacterium |
A | 0042802 | molecular_function | identical protein binding |
A | 0045087 | biological_process | innate immune response |
A | 0060205 | cellular_component | cytoplasmic vesicle lumen |
A | 0070062 | cellular_component | extracellular exosome |
A | 0120162 | biological_process | positive regulation of cold-induced thermogenesis |
A | 0140315 | molecular_function | iron ion sequestering activity |
A | 1903981 | molecular_function | enterobactin binding |
Functional Information from PROSITE/UniProt
site_id | PS00213 |
Number of Residues | 14 |
Details | LIPOCALIN Lipocalin signature. NFQdnQFQGKWYVV |
Chain | Residue | Details |
A | ASN22-VAL35 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U |
Chain | Residue | Details |
A | TYR53 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0007744|PDB:3CMP |
Chain | Residue | Details |
A | TYR107 | |
A | LYS135 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15642259, ECO:0007744|PDB:1X89, ECO:0007744|PDB:1X8U |
Chain | Residue | Details |
A | LYS126 | |
A | TYR139 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:7683678 |
Chain | Residue | Details |
A | GLN2 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10684642, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7683678, ECO:0007744|PDB:1DFV, ECO:0007744|PDB:1QQS |
Chain | Residue | Details |
A | ASN66 |