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1NG1

N AND GTPASE DOMAINS OF THE SIGNAL SEQUENCE RECOGNITION PROTEIN FFH FROM THERMUS AQUATICUS

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
A0006614biological_processSRP-dependent cotranslational protein targeting to membrane
A0016887molecular_functionATP hydrolysis activity
A0048500cellular_componentsignal recognition particle
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CD A 701
ChainResidue
AGLU11
AGLU33
AGLU46
AASP50

site_idAC2
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CD A 751
ChainResidue
AGLU285

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CD A 752
ChainResidue
AHIS261
AACY952
AHOH1126
AHOH1127

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 902
ChainResidue
ATHR112
AGDP900
AHOH1138
AHOH1139
AHOH1140
AHOH1141

site_idAC5
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 912
ChainResidue
AHOH1142
AHOH1143
AHOH1144
AHOH1145
AHOH1146
AHOH1147

site_idAC6
Number of Residues21
DetailsBINDING SITE FOR RESIDUE GDP A 900
ChainResidue
ALEU106
AGLY108
ASER109
AGLY110
ALYS111
ATHR112
ATHR113
ALYS117
ALYS246
AASP248
AGLY271
AVAL272
ASER273
AGLU274
AMG902
AHOH1000
AHOH1030
AHOH1049
AHOH1138
AHOH1139
AHOH1140

site_idAC7
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 970
ChainResidue
AARG32
AGLU33
AARG36
AGLU53
AHOH982
AHOH1105
AHOH1125

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 971
ChainResidue
AASP42
ATHR222
AGLN224
AGLU225

site_idAC9
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 972
ChainResidue
AALA176
AARG181
AHOH996

site_idBC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ACY A 950
ChainResidue
ALYS62
AARG128
AARG181

site_idBC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ACY A 951
ChainResidue
ALYS28
ALEU31
AARG35
AARG56

site_idBC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ACY A 952
ChainResidue
AGLU46
AHIS261
ACD752

site_idBC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ACY A 953
ChainResidue
AARG98
ALEU100
AARG169
AVAL172
ALEU209

Functional Information from PROSITE/UniProt
site_idPS00300
Number of Residues14
DetailsSRP54 SRP54-type proteins GTP-binding domain signature. PIyFAGVSEkPegL
ChainResidueDetails
APRO266-LEU279

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00306
ChainResidueDetails
ALEU106
ATHR188
ALYS246

226707

PDB entries from 2024-10-30

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